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Titlebook: Neurotransmitter and Dementia; C. G. Gottfries,S. Nakamura Conference proceedings 1990 Springer-Verlag Wien 1990 Alzheimer.CNS.alzheimer‘s

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發(fā)表于 2025-3-21 17:05:45 | 只看該作者 |倒序瀏覽 |閱讀模式
書目名稱Neurotransmitter and Dementia
編輯C. G. Gottfries,S. Nakamura
視頻videohttp://file.papertrans.cn/665/664581/664581.mp4
叢書名稱Journal of Neural Transmission. Supplementa
圖書封面Titlebook: Neurotransmitter and Dementia;  C. G. Gottfries,S. Nakamura Conference proceedings 1990 Springer-Verlag Wien 1990 Alzheimer.CNS.alzheimer‘s
描述Neurotransmitter changes taking place in the brain of patients with dementia disorders, mainly Alzheimer type dementia, are reported. Their role in the pathogenesis of Alzheimer‘s disease is discussed; and the neurochemical changes are considered as a base for formulating treatment strategies. By studying markers in the cerebrospinal fluid, diagnostic methods may be achieved that will aid in diagnosing subgroups of dememtia.
出版日期Conference proceedings 1990
關鍵詞Alzheimer; CNS; alzheimer‘s disease; brain; dementia; metabolism; neurons; neurotransmitter; research
版次1
doihttps://doi.org/10.1007/978-3-7091-3345-3
isbn_softcover978-3-211-82190-9
isbn_ebook978-3-7091-3345-3Series ISSN 0303-6995
issn_series 0303-6995
copyrightSpringer-Verlag Wien 1990
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,Changes in signal transduction in Alzheimer’s disease,tire plaques and surrounding glial cells. Anti-PKC (.I) stained dystrophic plaque neurites. Anti-PKC (.II) stained the amyloid-containing portions of plaques. These results suggest an involvement of second messenger cascades in the pathogenesis of AD in addition to neurotransmitters and their receptors.
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Conference proceedings 1990e pathogenesis of Alzheimer‘s disease is discussed; and the neurochemical changes are considered as a base for formulating treatment strategies. By studying markers in the cerebrospinal fluid, diagnostic methods may be achieved that will aid in diagnosing subgroups of dememtia.
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,Subcellular distribution of acetylcholinesterase in Alzheimer’s disease: abnormal localization and fuged at 100,000 . for 60 min. More than 50% of AChE activity was detected in the supernatant fraction. AChE in the supernatant solution showed a property of G4 isozyme. AChE might probably be anchored to the senile plaque through its collagen tail and be solubilized with collagenase or protease, producing a G4 isozyme.
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Journal of Neural Transmission. Supplementahttp://image.papertrans.cn/n/image/664581.jpg
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https://doi.org/10.1007/978-3-7091-3345-3Alzheimer; CNS; alzheimer‘s disease; brain; dementia; metabolism; neurons; neurotransmitter; research
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