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Titlebook: Neurotransmitter Enzymes; Alan A. Boulton,Glen B. Baker,Peter H. Yu Book 1986 Springer Science+Business Media New York 1986

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11#
發(fā)表于 2025-3-23 13:19:25 | 只看該作者
Phenylalanine Hydroxylase, Tyrosine Hydroxylase, and Tryptophan Hydroxylase,anine 4-monooxygenase (phenylalanine hydroxylase, PAH, EC 1.14.16.l), tyrosine 3-monooxygenase (tyrosine hydroxylase, TH, EC 1.14.16.2), anthranilate 3-monooxygenase (EC 1.14.16.3), and tryptophan 5-monooxygenase (tryptophan hydroxylase, TPH, EC 1.14.16.4). All four enzymes are also known as iron-pr
12#
發(fā)表于 2025-3-23 15:44:08 | 只看該作者
Aromatic ,-Amino Acid Decarboxylase,These compounds and their derivatives are important regulatory substances. Although consensus has been difficult to reach, it appears that only two enzymes catalyze the decarboxylation of aromatic amino acids in mammals. first, histidine decarboxylase (EC 4.1.1.22), a very specific enzyme; and secon
13#
發(fā)表于 2025-3-23 20:41:48 | 只看該作者
,Dopamine β-Hydroxylase,is a copper-containing monooxygenase that catalyzes hydroxylation of a phenylethylamine (mainly dopamine in vivo) at the β-C of the side chain to a phenylethanolamine [noradrenaline (NA) from dopamine], using molecular oxygen and ascorbic acid as an electron donor. DBH localizes in noradrenergic and
14#
發(fā)表于 2025-3-23 23:43:15 | 只看該作者
Monoamine Methyltransferases,zes the biosynthesis of norepinephrine [noradrenaline; (NA)] to epinephrine [adrenaline; (A)] in the presence of .-adenosyl-.-methionine (SAM) as the methyl donor. The enzyme is localized mainly in the adrenal medulla and in small amounts in discrete brain regions containing A cell bodies and nerve
15#
發(fā)表于 2025-3-24 04:03:46 | 只看該作者
Histamine ,-Methyltransferase,igations, and although these studies have provided a fundamental understanding of this enzyme, HNMT has not been the subject of a comprehensive review or analysis. This is surprising since HNMT and diamine oxidase (DAO; EC 1.3.4.6) are the only known enzymes that terminate the physiologic activity o
16#
發(fā)表于 2025-3-24 09:00:15 | 只看該作者
-Histidine Decarboxylase,,., .; .). One of the key pieces of experimental evidence has been the demonstration that synthesis of the amine in CNS depends on a specific enzyme, .-histidine decarboxylase (HDC) (.), localized in a specific set of neurons, therefore constituting a reliable marker.
17#
發(fā)表于 2025-3-24 13:37:09 | 只看該作者
Monoamine Oxidase,eurotransmitters and neuromodulators, as well as exogenous bioactive monoamines. It was first characterized by (.) as monoamines (TA) oxidase and was later called monoamine oxidase by (.). A considerable interest in the enzyme developed after the discovery that MAO inhibitors alleviated clinical sym
18#
發(fā)表于 2025-3-24 18:07:17 | 只看該作者
19#
發(fā)表于 2025-3-24 22:33:11 | 只看該作者
20#
發(fā)表于 2025-3-24 23:41:57 | 只看該作者
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