Titlebook: Neurotox ’91; Molecular Basis of D I. R. Duce Book 1992 SCI 1992 Calcium.Glutamat.Nervous System.natural product.neural network.pesticide.p

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Conus Peptides and Biotechnologyiotechnological applications at the present time. Although there is a remarkable pharmacological diversity of conotoxins, each peptide toxin is very specifically targeted.. In certain cases, conotoxins are able to discriminate between closely related subtypes of a receptor target.

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The GABA Activated Cl- Channel in Insects as Target for Insecticide Action: a Physiological Studyed Na. channel, the cholinergic synapse and the GABAergic synapse. The idea that one major inhibitory system in insects, the GABA activated Cl. channel is an important target of insecticide action is based on the observation that cyclohexane and cyclodiene insecticides antagonise GABA activated Cl.c

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Pharmacology of the , Nervous Systembout half are parasitic. Their occurrence world-wide is phenomenal: a quarter or more of the world‘s population are afflicted with nematode infections, they cause considerable losses in livestock, and the small plant parasitic nematodes are responsible for widespread crop damage.

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The Peptidergic Neuron: Possible New Molecular Targetsnovel methods of pest control. Neuropeptides represent the largest and most diverse class of neurotransmitters and neurohormones in the nervous systems of both vertebrates and invertebrates.. They are responsible for regulating such diverse and essential biological processes as development and matur

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The Molecular Biology of Potassium Channels and Mutations that Alter the Selectivity of the Poreloning of a large family of these channels. Originally cloned in ., homologs in other species have been isolated as well. Diversity within the family is generated by several mechanisms: six different classes of K+ channel genes, multiple closely related genes within a single class, and alternative R

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FMRFamide-Related Peptides: Organisation and Expression of the Gene in the Snail Lymnaea the single letter abbreviations for its constituent amino acids (Phe-Met-Arg-Phe-NH.). FMR Famide was originally isolated from the sunray Venus clam . by Price and Greenberg in 1977,. and since then attempts have been made to detect FMR Famide in many diverse phyla. Authentic FMR Famide appeared to

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Expression of Neurotransmitter Receptors in Insect Cells Using Baculovirus Vectors processed and targeted protein. To date the most popular expression systems for receptors have been the injection of DNA or mRNA into . oocytes,. or the use of vectors to transform .,. yeast. or mammalian cells, e. g. fibroblasts.. One of the main disadvantages of these systems is that often only v