Titlebook: Neuroreceptor Mechanisms in Brain; Shozo Kito,Tomio Segawa,Richard W. Olsen Book 1991 The Editor(s) (if applicable) and The Author(s), und

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,Expression of G-Protein α-Subunit cDNA,Molecular cloning of G-protein α-subunit (Gα) has revealed the existence of nine or more Gα genes and a high degree of amino acid sequence homology. However, it is not clear whether each Gα transduces a distinct signal or not.

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Book 1991 the brain is progressing at an unprecedented pace. The sym- posium also marked my retirement as Professor and Chairman of the Third Department of Internal Medicine, Hiroshima University School of Medicine, and a new beginning as a Professor of the University of the Air. The symposium was remarkably

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Transmitter-Activated Ion Channels as the Target of Chemical Agents,ol, and n-decanol also exerted the same type of effect, with the potency and efficacy increasing with lengthening of the carbon chain..The GABA receptor-channel complex has also been shown to be an important target site of certain insecticides. The type II pyrethroids deltamethrin and fenvalerate au

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Chemical Kinetic Investigations of the Channel-Opening Process of Neurotransmitter Receptors,hesized caged neurotransmitters bonded to a photo-dissociative o-nitrobenzyl group with the nitrogen atom. These compounds have shown relatively fast photolysis and have been useful for the study of neuronal receptors.

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Serotonin Receptor Subtypes in Brain: Ligand Binding Properties and Coupling with G Proteins, their coupling (Katada et al., 1986b; Kitamura and Nomura, 1987; Nomura et al., 1988). To classify 5-HT receptor subtypes in the CNS from binding characteristics and the aspect of coupling properties of these receptors with G proteins, we here examined the effects of GTPyS, NEM and several 5-HT rec