Titlebook: Neuroprotection and Regeneration of the Spinal Cord; Kenzo Uchida,Masaya Nakamura,Yoshiaki Toyama Book 2014 Springer Japan 2014 OPLL.biome

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Autophagy in Spinal Cord Injury: Pathogenic Roles and Therapeutic Implicationsogical processes in many diseases. We previously investigated alternation of autophagic activity in damaged neural tissue after SCI. It was also examined whether administration of rapamycin to promote autophagy can induce neuroprotective effect in SCI. Our results of these studies demonstrated that

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The Role of the Endoplasmic Reticulum Stress Response in Neural Apoptosis of the Injured Spinal Cordtem proliferate around the lesion epicenter. However, most of these cells fail to differentiate into mature oligodendrocytes, hindering their potential for remyelination and functional recovery. One of the major inhibitory factors of OPC differentiation is apoptosis, which also leads to expansion of

Abutment

Roles of Microglia in Spinal Cord Injurymental spinal cord injuries, proliferation of microglia in the injured site has been detected. Activated microglia release many substances which modulate secondary neuronal degeneration and regeneration after spinal cord injury. However, whether microglia are good or bad is under debate. In the acut

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congenial

Biomechanical Analysis of Compressive Myelopathy: The Influence of Morthometry of the Spinal Cordd a three-dimensional finite element method (3D-FEM) to analyze the stress distributions of the spinal cord under three cross-sectional cord morphometry. Experimental condition for the 3D-FEM spinal cord, anterior compression shape (central, lateral, and diffuse types), and invagination of the ligam

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Morphological Changes in Anterior Horn Cells, Immunoreactivity to Neurotrophic Factors, and Neuronalreactive astrocytosis in 70 tiptoe-walking Yoshimura (./.) mice that develop calcification at C1–C2 vertebral level compressing the spinal cord. At the level of compression, the area of neuronal soma, total length of dendrites, and numbers of wheat germ agglutinin-horseradish peroxidase (WGA-HRP)-la

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sed-rate

Microarray Analysis of Expression of Cell Death-Associated Genes in Spinal Cord Cells with Cyclic Tenvestigate in vivo. Therefore, we have investigated the effect of cyclic tensile strain on cultured spinal cord cells from E15 Sprague–Dawley rats. Microarray analysis of gene expression and categorization of identified genes were performed using Gene Ontology (GO) and Kyoto Encyclopedia of Genes an