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Titlebook: Neuronal Growth Factors; Mark Bothwell Book 1991 The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verl

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發(fā)表于 2025-3-21 19:12:42 | 只看該作者 |倒序瀏覽 |閱讀模式
書目名稱Neuronal Growth Factors
編輯Mark Bothwell
視頻videohttp://file.papertrans.cn/665/664267/664267.mp4
叢書名稱Current Topics in Microbiology and Immunology
圖書封面Titlebook: Neuronal Growth Factors;  Mark Bothwell Book 1991 The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verl
描述A host of environmental factors regulate the embryonic development of neurons. In adults, the survival of neurons, the regeneration of damaged axons, and plastic changes in axonal arborization are also controlled by a complex array of environmental cues. An important category of regulatory influences involves target-derived hormone-like peptides act- ing on neuronal cell surface receptors. Nerve growth factor (NGF) was the first such factor to be characterized (LEVI- MONTALCINI and HAMBURGER 1953) and has served as the model against which all similar factors are compared. A number of factors with properties similar to NGF have been described with activities toward differing populations of neurons. Many of these factors have been characterized only poorly at the biochemical level. However, several factors have been charac- terized to the extent that molecular clones are available and complete amino acid sequences are known. These include: three structurally related factors, NGF itself (SCOTT et al. 1983), brain-derived neurotrophic factor (BDNF) (LEIBROCK et al. 1989), and neurotrophin-3 (NT-3) (MAISONPIERRE et al. 1990; HOHN et al. 1990); ciliary neurotrophic factor (CNTF) (LIN et
出版日期Book 1991
關(guān)鍵詞Alzheimer; Nervous System; Wachstum; Wachstumsfaktor; Wachstumsfaktoren; alzheimer‘s disease; biochemistry
版次1
doihttps://doi.org/10.1007/978-3-642-75747-1
isbn_softcover978-3-642-75749-5
isbn_ebook978-3-642-75747-1Series ISSN 0070-217X Series E-ISSN 2196-9965
issn_series 0070-217X
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE
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發(fā)表于 2025-3-21 20:23:37 | 只看該作者
https://doi.org/10.1007/978-3-642-75747-1Alzheimer; Nervous System; Wachstum; Wachstumsfaktor; Wachstumsfaktoren; alzheimer‘s disease; biochemistry
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The Membrane Receptor for Nerve Growth Factor,markable set of reactions in responsive cells, including changes in gene expression, activation of neurotransmitter enzymes, and stimulation of neuronal processes. These many events lead ultimately to the survival and maintenance of selective neuronal cell populations.
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Dissecting the Mode of Action of a Neuronal Growth Factor, exemplified by NGF and FGF, encompass an enormous range of actions, making elucidation of the underlying molecular mechanisms a formidable task. However, a multidisciplinary approach has been brought to bear on this task, and studies of neuronal growth factor action have gained from as well as contributed insights to other fields.
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