Titlebook: Neurogenesis in the Adult Brain II; Clinical Implication Tatsunori Seki (Professor),Kazunobu Sawamoto (Prof Book 2011 Springer 2011

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Adult Neurogenesis and Neuronal Subtype Specification in the Neocortex,ircuitry. However, recent development of new experimental techniques and approaches has shown that the adult brain contains neural precursors (sometimes termed “neural stem cells”; comprising partially heterogeneous, fate-restricted progenitors plus theoretical primitive totipotent CNS “stem cells”)

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olecular biology of adult neurogenesis.Chapters on the clini.The discovery of adult neurogenesis caused a paradigm shift in the neurosciences. For more than 100 years, it was believed that adult neurons do not regenerate. Joseph Altman and Fernando Nottebohm found proof to the contrary and changed t

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,Adult Neurogenesis in Parkinson’s Disease,is in genetic PD models. The enhancement of progenitor cells may represent a potential new source of cells for replacement therapy in PD. In this review, possible treatments to enhance neurogenesis in PD models are also described.

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Depression,adult hippocampus is involved in pathogenesis of depression and an enhancement of hippocampal neurogenesis is one of mechanisms for the successful antidepressant treatment. This article examines this hypothesis with experimental and clinical data.

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