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Titlebook: Neuroepigenomics in Aging and Disease; Raul Delgado-Morales Book 2017 Springer International Publishing AG 2017 epigenomics.genomics.Neuro

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發(fā)表于 2025-3-21 18:39:01 | 只看該作者 |倒序瀏覽 |閱讀模式
書目名稱Neuroepigenomics in Aging and Disease
編輯Raul Delgado-Morales
視頻videohttp://file.papertrans.cn/665/664037/664037.mp4
概述One of the first books covering the major epigenetic changes on brain disorders throughout the entire lifespan of the patients.An invaluable reference that supplies extensive coverage of the role of a
叢書名稱Advances in Experimental Medicine and Biology
圖書封面Titlebook: Neuroepigenomics in Aging and Disease; Raul Delgado-Morales Book 2017 Springer International Publishing AG 2017 epigenomics.genomics.Neuro
描述Epigenetic mechanisms (DNA modifications, histone alterations and non-coding RNAs) are crucial for transcriptional regulation and alterations of the “physiological epigenome” are increasingly associated with human diseases.?During the last decade the emerging field of neuroepigenomics have started to impact?tremendously?in areas such learning and memory, addiction or neurodegeneration. This expert volume covers the role of epigenetic molecular mechanism in regulation of central nervous system’s function,?one of the most exciting areas of contemporary molecular neuroscience. The book describes the current knowledge on the epigenetic basis of human disease covering the complete lifespan: from neurodevelopment/childhood (Rett Syndrome, Rubinstein-Taybi, autism), adolescence (eating disorders, drug addiction, anxiety), adulthood (depression, schizophrenia,?amyotrophic lateral sclerosis,?Huntington’s?disease) and elderly (Alzheimer’s disease, Parkinson’s disease)..The book also covers the three major players on neuroepigenomic mechanisms: histones alterations, DNA modifications and non-coding RNAs, their roles at the molecular and cellular level and the impact of their alterations on ne
出版日期Book 2017
關(guān)鍵詞epigenomics; genomics; Neurodegenerative; Diseases; microRNAs; modifications; Proteomics; gene expression
版次1
doihttps://doi.org/10.1007/978-3-319-53889-1
isbn_softcover978-3-319-85266-9
isbn_ebook978-3-319-53889-1Series ISSN 0065-2598 Series E-ISSN 2214-8019
issn_series 0065-2598
copyrightSpringer International Publishing AG 2017
The information of publication is updating

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Rubinstein-Taybi Syndrome and Epigenetic AlterationsNature 376:348–351, 1995). CBP was demonstrated to possess an intrinsic histone acetyltransferase activity (Ogryzko et al., Cell 87:953–959, 1996) that is required for CREB-mediated gene expression (Korzus et al., Science 279:703–707, 1998). The intrinsic protein acetyltransferase activity in CBP mi
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Histone Modifications in Major Depressive Disorder and Related Rodent Modelse. histone acetylation and methylation, in the context of MDD and related animal models. We discuss new treatment options which have been based on these findings, including histone deacetylase inhibitors (HDACis) and drugs targeting specific histone marks, closely linked to psychiatric disease. In t
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Epigenetics of Huntington’s Disease (Front Neurosci 9:509, 2015). The rate-limiting mechanism(s) of neurodegeneration in HD still remains elusive: many different processes are commonly disrupted in HD cell lines and animal models, as well as in HD patient cells (Eur J Neurosci 27:2803–2820, 2008); however, epigenetic-chromatin deregu
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Book 2017ington’s?disease) and elderly (Alzheimer’s disease, Parkinson’s disease)..The book also covers the three major players on neuroepigenomic mechanisms: histones alterations, DNA modifications and non-coding RNAs, their roles at the molecular and cellular level and the impact of their alterations on ne
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angelegte Festschrift für Reinhold Hedtke schl?gt die Brücke zwischen den zentralen sozialwissenschaftlichenBezugsdisziplinen Wirtschaftswissenschaften, Soziologie, Politikwissenschaft und Geographie sowie Geschichtswissenschaft, Philosophie und Erziehungswissenschaft.?. . . . .978-3-658-36995-8
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echen, realisiert werden k?nne, ohne die bestehenden politischen, wirtschaftlichen und gesellschaftlichen Bedingungen grundlegend zu ver?ndern. Und sie macht Vorschl?ge, in welche Richtung diese Ver?nderung gehen k?nnte.?978-3-658-17809-3978-3-658-17810-9Series ISSN 2626-6172 Series E-ISSN 2626-6180
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