| 書目名稱 | Neural Transplants | | 副標(biāo)題 | Development and Func | | 編輯 | John R. Sladek,Don M. Gash | | 視頻video | http://file.papertrans.cn/664/663758/663758.mp4 | | 圖書封面 |  | | 描述 | The story of mammalian neural transplantation really begins eighty-one years ago. In Chicago in December of 1903, a 34-year-old physician, Elizabeth Hopkins Dunn, working as a research assistant in neurology, initiated a series of experiments to examine the ability of neonatal rat cerebral tissue to survive transplantation into the brain of matched littermates. Out of 46 attempts, four clearly successful grafts were identified. The publication of Dunn‘s results in 1917, the first credible report to demonstrate the feasibility of mammalian CNS transplants, generated little interest. In fact, the next significant experiment in this field did not appear until 1930. The field continued to grow slowly and quietly as investigators gradually realized the value of neural trans- plantation to study problems of development and plasticity in the mammalian nervous system. With the discovery in 1979 that grafted neurons were capable of appropriate and functional interactions with the host brain, interest in neural transplantation esca- lated sharply. The extraordinary opportunities created by using functional neural trans- plants in investigating basic issues in neurobiology, as well as the cli | | 出版日期 | Book 1984 | | 關(guān)鍵詞 | ELIZA; brain; nervous system; neurobiology; neurology; neurons | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-4684-4685-2 | | isbn_softcover | 978-1-4684-4687-6 | | isbn_ebook | 978-1-4684-4685-2 | | copyright | Plenum Press, New York 1984 |
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