Titlebook: Neural Repair; Methods and Protocol Vardan T. Karamyan,Ann M. Stowe Book 2023 The Editor(s) (if applicable) and The Author(s), under exclus

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Multi-exposure Speckle Imaging for Quantitative Evaluation of Cortical Blood Flow speckle imaging (MESI) is an extension of LSCI that allows for reproducible and quantifiable measurements of flow. MESI has the potential to provide quantitative cerebral blood flow information in both preclinical and clinical applications; in fact, MESI can be extended to resolve the flow dynamics

white-matter

Wide-Field Optical Imaging in Mouse Models of Ischemic Stroke to functional recovery. For example, acutely after stroke, changes in functional brain organization relate to initial deficit and are predictive of recovery potential. During recovery, the reemergence and restoration of connections lost due to stroke correlate with recovery of function. Thus, infor

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Quantitative Spatial Mapping of Axons Across Cortical Regions to Assess Axonal Sprouting After Strokonal collaterals, a phenomenon that is restrained in the normal adult brain. Enhancements in sprouting of axons have been linked with enhancements in motor function. Here, we describe a method developed in-house using standard reagents to map and quantitatively assess differential sprouting response

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Quantitative Evaluation of Cerebral Microhemorrhages in the Mouse Brainn mouse models, detection of cerebral microhemorrhages involves the use of magnetic resonance imaging and/or postmortem neuropathology techniques including hematoxylin and eosin (H & E) staining to detect extravasated red blood cells and fresh/acute microhemorrhages and Prussian blue staining to det

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In Vivo Evaluation of BBB Integrity in the Post-stroke Brainbrain from undesired compounds and proteins from the blood; however, BBB impairment is involved in various pathological conditions including stroke. In vivo evaluation of BBB integrity in the post-stroke brain is important for investigating stroke-induced CNS pathogenesis and developing CNS-targeted

Spinal-Fusion

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