Titlebook: Natural Products from Actinomycetes; Diversity, Ecology a Ravishankar V. Rai,Jamuna A. Bai Book 2022 The Editor(s) (if applicable) and The

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Polar Actinobacteria: A Source of Biosynthetic Diversity,the most extensively explored bacterial phyla, Actinobacteria from polar regions are still overlooked. In this chapter, the taxonomic diversity of Actinobacteria isolated from the poles, their associated secondary metabolites, and the diversity of biosynthetic genes that encode for polyketides and n

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Actinobacteria from Arid Environments and Their Biotechnological Applications,ative of arid environment, is known to harbour diverse Actinobacteria with biotechnological potential. These cultivable Actinobacteria are adapted with a special survival mechanism to combat various stresses in the desert biomes. Both the emergence of multidrug-resistant (MDR) diseases and the sharp

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Endophytic Actinobacteria in Biosynthesis of Bioactive Metabolites and Their Application in Improvi future of agriculture. Plants are associated with numerous microbes and possess a dynamic microbiome. Endophytic Actinobacteria (EA) are a prolific source of bioactive secretion and exudation products and offer renewed attention towards attaining sustainable agriculture. Endophytic Actinobacteria c

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An Overview on Natural Product from Endophytic Actinomycetes,reason, there is an urgent need to prevent these kinds of infections with natural sources. In this regard, endophytic actinomycete is an excellent reservoir for production of novel chemical metabolites with excellent byproduct in biomedical, pharmaceutical, and industrial applications. The endophyti

MANIA

Regulation of Secondary Metabolites Through Signaling Molecules in , antiviral drugs, herbicides, pesticides, insecticides, and immunosuppressants. Their biosynthesis is strictly controlled by small diffusible signaling molecules that constitute a signaling molecule/receptor regulatory systems. These signaling molecule/receptor regulatory systems are extensively stu

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Interlocking

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Metabolic Engineering of Actinomycetes for Natural Product Discovery, actinomycetal origin. However, discovery has slowed significantly since the so-called golden age of antibiotics in the 1940s–1960s. The expansion of genome sequencing has revealed many more undiscovered natural products which are often cryptic, or not produced under standard laboratory conditions d

季雨

Application of CRISPR/Cas9 Editing for Production of Secondary Metabolites in Actinomycetes,aks in genomes. Further, it can be directed to introduce either site-specific insertions or deletions and to replace genes in bacteria. It has been successfully used as a genome editing tool in ., . and .. The application of CRISPR/Cas9 for industrially relevant strains especially the actinomycetes,