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Titlebook: Natural Products Chemistry III; Atta-ur-Rahman,Philip William Quesne Conference proceedings 1988 Springer-Verlag Berlin Heidelberg 1988 al

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書目名稱Natural Products Chemistry III
編輯Atta-ur-Rahman,Philip William Quesne
視頻videohttp://file.papertrans.cn/662/661892/661892.mp4
圖書封面Titlebook: Natural Products Chemistry III;  Atta-ur-Rahman,Philip William Quesne Conference proceedings 1988 Springer-Verlag Berlin Heidelberg 1988 al
描述Natural product chemistry has undergone an explosive growth during the latter half of the current century. This has been brought about by a number of factors. One of these has been the growing number of sub- stances from natural sources which display interesting pharmacological activities. These include antibiotics, anti-tumor agents, immunostimu- lants, drugs affecting the cardiovascular and central nervous systems, analgesics etc. Another factor has been the improvements made in the technology of isolation processes which includes the development of such techniques as high pressure liquid chromatography which has al- lowed the rapid isolation of substances which were previously diffi- cult to obtain by classical procedures. The most important factor has been the development of new spectrosopic techniques which have opened up whole new vistas in this exciting field. Prominent in these advan- ces has been the advent of powerful superconducting magnets with very stable magnetic fields, and pulse NMR in which the duration, direction and phases of pulses can be accurately controlled by means of mini- computers. These have heralded the advent of two-dimensional NMR spec- troscopy which
出版日期Conference proceedings 1988
關(guān)鍵詞alkaloids; analgesics; biochemistry; cancer; chemistry; development; growth; metabolism; natural products; ni
版次1
doihttps://doi.org/10.1007/978-3-642-74017-6
isbn_softcover978-3-642-74019-0
isbn_ebook978-3-642-74017-6
copyrightSpringer-Verlag Berlin Heidelberg 1988
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Total Synthesis of Nitrogen-Containing Natural Products via Nitroso Diels-Alder Reaction,de variety of reducing agents, such as zinc in acetic acid, sodium or aluminum amalgam in ethanol, or hydrogen over catalysts, and normally result in cleavage of the N-O bond leading to the formation of 4-amino alcohols.
地板
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Isoquinoline Alkaloid Synthesis via Arynes,untered in some cases forced us to try modified or radically different approaches. As a result, we have developed a new synthetic procedure that is applicable to a variety of different kinds of isoquinoline alkaloids.
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Applications of NMR in Biochemistry and Biosynthesis,2a,b]. The NMR method also uniquely defines HMB as the substrate for the second enzyme, uro’gen III cosynthetase. In the absence of the latter enzyme, the cyclization of the head-to-tail tetrapyrrole HMB takes place spontaneously. The deep-seated intra-molecular rearrangement of HMB to uro’gen III can now be studied by this technique.
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Synthetic, Multi-Deuteriated Cholesterol as a Quantitative Probe of the Formation of Cholesterol Oxn detection (GC-FID) and combined gas chromatography-mass spectrometry (GC-MS) have been used. Quantitation with an accuracy of 5% or better at the low part per million level for some of the common oxidation products is demonstrated.
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Stereochemical Studies on Pre-Anthraquinones and Dimeric Anthraquinone Pigments, of many neutral anthraquinones. The possibility that 5 is formed from 1 by a concerted loss of water and CO. has also to be considered. On the other hand, 2 can be converted into endocrocin (3) which serves as precursor to other anthraquinone carboxylic acids.
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