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Titlebook: Natural Products; Drug Discovery and T Lixin Zhang,Arnold L. Demain Book 2005 Humana Press 2005 cancer.drug.drug delivery.drug discovery.re

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發(fā)表于 2025-3-21 16:36:53 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱Natural Products
副標(biāo)題Drug Discovery and T
編輯Lixin Zhang,Arnold L. Demain
視頻videohttp://file.papertrans.cn/662/661890/661890.mp4
概述Includes supplementary material:
圖書封面Titlebook: Natural Products; Drug Discovery and T Lixin Zhang,Arnold L. Demain Book 2005 Humana Press 2005 cancer.drug.drug delivery.drug discovery.re
描述A fresh examination of the past successes of natural products as medicines and their new future from both conventional and new technologies. High-performance liquid chromatography profiling, combinatorial synthesis, genomics, proteomics, DNA shuffling, bioinformatics, and genetic manipulation all now make it possible to rapidly evaluate the activities of extracts as well as purified components derived from microbes, plants, and marine organisms. The authors apply these methods to new natural product drug discoveries, to microbial diversity, to specific groups of products (Chinese herbal drugs, antitumor drugs from microbes and plants, terpenoids, and arsenic compounds), and to specific sources (the sea, rainforest, and endophytes). These new opportunities show how research and development trends in the pharmaceutical industry can advance to include both synthetic compounds and natural products, and how this paradigm shift can be more productive and efficacious.
出版日期Book 2005
關(guān)鍵詞cancer; drug; drug delivery; drug discovery; research
版次1
doihttps://doi.org/10.1007/978-1-59259-976-9
isbn_softcover978-1-61737-533-0
isbn_ebook978-1-59259-976-9
copyrightHumana Press 2005
The information of publication is updating

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Natural Products and Drug Discoveryhypocholesterolemic agents, immunosuppressive agents, antimigraine agents, and so on. A number of these products were first discovered as antibiotics that failed in their development as such, or as mycotoxins.
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發(fā)表于 2025-3-22 11:57:49 | 只看該作者
Automated Analyses of HPLC Profiles of Microbial Extractsmethod for building libraries of natural products for drug discovery. Specific computer analyses of high-performance liquid chromatography chromatograms from organic extracts of fermented microorganisms can be used as a tool for increasing chemical diversity of collections, media improvement, evalua
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Manipulating Microbial Metabolites for Drug Discovery and Production new ones. Expression of the native or engineered polyketide synthase genes, as well as others that govern metabolite formation, in heterologous hosts is an important aspect of developing commercial systems for drug production. This chapter highlights advances made by Kosan Biosciences and some othe
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Challenges and Opportunities in the Chinese Herbal Drug Industryas made rapid progress over the past decades. This chapter provides a review of its current status, including challenges and opportunities, specifically with regard to modernization and globalization of TCM.
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Arsenic Trioxide and Leukemiaaturation towards granulocytic cells at the promyelocytic stage, was determined to be an excellent target for “Ailing-1” therapy. At the same time, there were reports of using the formula called “niu huang jie du pian” (containing xiong huang) or just using xiong huang (realgar) by itself to treat A
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