Titlebook: Natural Product-based Synthetic Drug Molecules in Alzheimer‘s Disease; Therapeutic & Theran Abha Sharma,Gyan Prakash Modi Book 2023 The Edi

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Huperzine-Based Derivatives: Design, Synthesis, and Anti-Alzheimer Activityaches, and multipotent naturally occurring agents have recently drawn attention in this regard. Huperzine A, derived from . is one amongst these. Chemically, it is an alkaloid containing quinolizidine with good potency and selectivity and reversible inhibition of acetylcholinesterase. Many analogs o

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Polyphenol: Development of Polyphenol-Inspired Derivatives Targeting Pathological Factors of ADch can help to improve cognitive function in AD patients. Due to their potential therapeutic efficacy, polyphenols are a key focus in medicinal chemistry for designing multi-targeted as well as single-targeted drug ligands against different therapeutic targets of AD. In this chapter, we have aimed t

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Vitamin-Based Derivatives for the Management of Alzheimer’s Diseasehat show potential to treat Alzheimer’s disease. Primarily these compounds act on nuclear receptors to activate ADAM10, inhibiting AChE or BuChE, neutralisation of ROS, inhibition of GSK-3, and amyloid-beta aggregation. Moreover, some can easily pass the BBB, which is crucial in targeting neurologic

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Natural Product-based Synthetic Drug Molecules in Alzheimer‘s DiseaseTherapeutic & Theran

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Natural Product-based Synthetic Drug Molecules in Alzheimer‘s Disease978-981-99-6038-5

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