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Titlebook: Nanomaterial; Impacts on Cell Biol David G. Capco,Yongsheng Chen Book 2014 The Editor(s) (if applicable) and The Author(s), under exclusive

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Engineered Nanoparticles Induced Brush Border Disruption in a Human Model of the Intestinal Epithelthe nanoscale. Moreover, their small size, and the ability to functionalize the outer nanoparticle surface makes them an ideal vector suited to traverse a number of physical barriers in the human body. While nanoparticles hold great promise for applications in cell biology and medicine, their downfa
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Nanoparticles: Cellular Uptake and Cytotoxicity,the biomedical applications of NPs, particularly for drug delivery. Various factors, whether differences in physical properties of NPs or variations in cell-membrane characteristics, influence NP-cell interactions and uptake processes. NP-cell membrane interactions may also influence intracellular t
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Atomic Force Microscopy Study of the Interaction of DNA and Nanoparticles,DNA interactions and explore the underlying chemical mechanisms. In this chapter, we demonstrated systematic experimental approaches based on atomic force microscope (AFM), coupled with modeling computation to probe the binding activity of NPs with DNA and the putative genotoxicity. Using quantum do
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