Titlebook: NF-kB/Rel Transcription Factor Family; Hsiou-Chi Liou Book 2006 Springer-Verlag US 2006 Immunity.protein.regulation.signal transduction.tr

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,Molecular Basis of Oncogenesis by NF-κB,g body of evidence also underscores their important role in the control of cellular gene expression, cell proliferation and apoptosis. Thus, it comes as no surprise that sustained Rel/NF-κB activity has emerged as a hallmark of many human cancers. Experimental evidence indicates a strong correlation

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,NF-κB in Human Cancers,oteins with other transcriptional regulators in the nucleus, and our ability to tract and abrogate NF-κB activity, effectively and specifically, remain the subject of intense research efforts in cancer therapy. While NF-κB activity is the principle subject of this chapter and the target of several e

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