| 書目名稱 | Muscle Biophysics | | 副標(biāo)題 | From Molecules to Ce | | 編輯 | Dilson E. Rassier | | 視頻video | http://file.papertrans.cn/642/641399/641399.mp4 | | 概述 | Chapters contributed by world leaders in their field.Material covers an updated, comprehensive inclusion of techniques in both cell and molecular biophysiology.Represents an excellent source of inform | | 叢書名稱 | Advances in Experimental Medicine and Biology | | 圖書封面 |  | | 描述 | Muscle contraction has been the focus of scientific investigation for more than two centuries, and major discoveries have changed the field over the years. Early in the twentieth century, Fenn (1924, 1923) showed that the total energy liberated during a contraction (heat + work) was increased when the muscle was allowed to shorten and perform work. The result implied that chemical reactions during contractions were load-dependent. The observation underlying the “Fenn effect” was taken to a greater extent when Hill (1938) published a pivotal study showing in details the relation between heat production and the amount of muscle shortening, providing investigators with the force-velocity relation for skeletal muscles. Subsequently, two papers paved the way for the current paradigm in the field of muscle contraction. Huxley and Niedergerke (1954), and Huxley and Hanson (1954) showed that the width of the A-bands did not change during muscle stretch or activation. Contraction, previously believed to be caused by shortening of muscle filaments, was associated with sliding of the thick and thin filaments. These studies were followed by the classic paper by Huxley (1957), in which he conce | | 出版日期 | Book 2010 | | 關(guān)鍵詞 | ATP; Herz; biophysics; cells; mechanics; physiology; skeletal muscle; temperature | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-4419-6366-6 | | isbn_softcover | 978-1-4614-2663-9 | | isbn_ebook | 978-1-4419-6366-6Series ISSN 0065-2598 Series E-ISSN 2214-8019 | | issn_series | 0065-2598 | | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines |
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