| 書(shū)目名稱 | Molecular and Clinical Advances in Anticancer Drug Resistance | | 編輯 | Robert F. Ozols | | 視頻video | http://file.papertrans.cn/639/638604/638604.mp4 | | 叢書(shū)名稱 | Cancer Treatment and Research | | 圖書(shū)封面 |  | | 描述 | The importance of drug resistance in cancer chemotherapy cannot be over- stated. The 500,000 patients who die every year from cancer in the United States have, in most cases, been treated with chemotherapy. Many of these patients responded initially to chemotherapy, but death resulted from the development of drug-resistant tumors. In the first volume in the series. Drug Resistance in Chemotherapy the results of comprehensive laboratory studies aimed at understanding the mechanisms for resistance to individual agents and to the development of broad cross-resistance were described. In the past 2 years there has been substantial progress in understanding the molecular biology associated with these mechanisms of drug resistance. For the first time we are starting to understand which mechanisms are playing an im- portant role in human tumors, and even more importantly, clinical trials have recently been initiated in an effort to reverse specific forms of drug resistance. The purpose of this volume is to describe the new advances, both at the molecular level and in the clinic regarding mechanisms of drug resistance and potential ways this resistance can be circumvented. This volume is fo | | 出版日期 | Book 1991 | | 關(guān)鍵詞 | DNA; cancer; cell; chemotherapy; clinical trial; drug; drug resistance; molecular biology; research; resistan | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-4615-3872-1 | | isbn_softcover | 978-1-4613-6726-0 | | isbn_ebook | 978-1-4615-3872-1Series ISSN 0927-3042 Series E-ISSN 2509-8497 | | issn_series | 0927-3042 | | copyright | Springer Science+Business Media New York 1991 |
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