| 書(shū)目名稱(chēng) | Molecular Defects in Cardiovascular Disease | | 編輯 | Naranjan S. Dhalla,Makoto Nagano,Bohuslav Ostadal | | 視頻video | http://file.papertrans.cn/639/638162/638162.mp4 | | 概述 | Outlines novel targets for the treatment of cardiovascular diseases.Elucidates the role of biochemical insults and metabolic derangements in altering gene expression.Provides an understanding of the m | | 圖書(shū)封面 |  | | 描述 | .Molecular Defects in Cardiovascular Disease?provides an in-depth discussion of the molecular mechanisms underlying the genesis of cardiovascular defects and the implications this has on current and emerging targeted therapeutics.? Divided into three sections, this book covers the scientific foundations of our present understanding as well as the array of clinical manifestations and their treatment.? The first section covers Molecular Mechanisms of Heart Disease, with discussion of the development of cardiovascular dysfunction.? The remaining two sections provide a more clinical focus.? The second, Cardiac Hypertrophy and Heart Failure deals with metabolic derangements, Ca.2+. handling, and subcellular remodeling. ?It illustrates the wide variety of molecular defects which may serve as targets associated with the transition from cardiac hypertrophy to advanced heart failure.? The third section, Hypertension and Diabetes, provides molecular rationale for the pathogenesis of hypertension and diabetic cardiomyopathy, as well as highlighting the importance of hormones toward this end.?.A necessary resource for clinicians and researchers, this book elucidates the experimental basis of t | | 出版日期 | Book 2011 | | 關(guān)鍵詞 | Cardiac; Cardiovascular; Genes; Genetics; Heart | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-4419-7130-2 | | isbn_softcover | 978-1-4939-4115-5 | | isbn_ebook | 978-1-4419-7130-2 | | copyright | Springer Science+Business Media, LLC 2011 |
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