Titlebook: Modelling Proteasome Dynamics in a Bayesian Framework; Sabine Stübler Book 2017 The Editor(s) (if applicable) and The Author(s), under exc

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2625-3577 transport and active site-related parameters applying an existing computational model. In a second step, the author extends this model to be able to describe the influence of proteasome inhibitors in .in vitro .experiments. The computational model, which describes the hydrolysis of short fluorogeni

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2625-3577 oach. The dynamics of proteasome inhibitors are included into the model in order to demonstrate how to modulate the inhibitor’s transport parameters for strong or isoform-specific inhibition..978-3-658-20166-1978-3-658-20167-8Series ISSN 2625-3577 Series E-ISSN 2625-3615

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Book 2017g computational model. In a second step, the author extends this model to be able to describe the influence of proteasome inhibitors in .in vitro .experiments. The computational model, which describes the hydrolysis of short fluorogenic peptides by the 20S proteasome, is calibrated to experimental d

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