| 書目名稱 | Mitochondrial DNA and Diseases | | 編輯 | Hongzhi Sun,Xiangdong Wang | | 視頻video | http://file.papertrans.cn/636/635053/635053.mp4 | | 概述 | Introduces the basic information of mtDNA.Summarize the latest development of mtDNA and disease.Focus on mtDNA biology and the roles of mtDNA in disease.Includes supplementary material: | | 叢書名稱 | Advances in Experimental Medicine and Biology | | 圖書封面 |  | | 描述 | .The book describes molecular principles and mechanisms by which mitochondrial DNA (mtDNA) can drive the occurrence of diseases and the latest understanding of mtDNA biology. The book explores roles of mtDNA mutation and genetic changes in cancer, with a special focus on lung cancer, and the significance of approach, application, and bioethics of mtDNA sequencing. ?Authors made a great effort to overview roles of mtDNA signaling pathways, base excision repair, methylation, USP30-mediated regulation, mitochondrial ribosome, autophagy pathways, or ROS-dependent signaling in the pathogenesis, diagnosis, prevention and treatment of diseases. It also demonstrates the importance of basic mitochondrial genetics and the relationship between mutations and disease phenotypes and ageing. This book covers not only the basic information of mtDNA, the relationship of mtDNA and disease, but also mtDNA in stem cell and mitochondria and metabolism etc. The book is written for biological and clinicalstudents and researchers in the field of mtDNA–associated diseases.. | | 出版日期 | Book 2017 | | 關(guān)鍵詞 | mitochondrial DNA; lung diseases; mitochondrial DNA repair; mitochondria and metabolism; mitochondrial h | | 版次 | 1 | | doi | https://doi.org/10.1007/978-981-10-6674-0 | | isbn_softcover | 978-981-13-4929-4 | | isbn_ebook | 978-981-10-6674-0Series ISSN 0065-2598 Series E-ISSN 2214-8019 | | issn_series | 0065-2598 | | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapor |
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