| 書(shū)目名稱 | Minimal Residual Disease in Acute Leukemia | | 編輯 | B. L?wenberg,A. Hagenbeek | | 視頻video | http://file.papertrans.cn/635/634517/634517.mp4 | | 叢書(shū)名稱 | Developments in Oncology | | 圖書(shū)封面 |  | | 描述 | The objective of the treatment of acute leukemia involves the eradication of all neoplastic cells, including the last one. Ideally, treatment should be controlled by monitoring cell kill. If the last cells could be discovered and their biological properties be determined, the qualitative and quantitative effects of treatment should be directly evaluable. This should ultimately permit a calculated tumor cell reduction thereby avoiding overtreatment and excessive toxicity and thus providing a basis for individualized antileukemic treatment. In recent years several new developments have contributed to the selective discovery of minimal numbers of leukemic cells which are hidden among the normal cells in the marrow cavities. These methods are the first steps to the realization of the therapeutic goals indicated above. They include the production and ap- plication of monoclonal antibodies against differentiation antigens on the cell sur- face, the use of pulse cytophotometry - and cell sorter techniques, the employment of cytogenetics, the development of culture techniques for selective growth of precursor cells and several others. These methodologies offer prospects for refined diagnos | | 出版日期 | Book 1984 | | 關(guān)鍵詞 | leukemia | | 版次 | 1 | | doi | https://doi.org/10.1007/978-94-009-5670-4 | | isbn_softcover | 978-94-010-9002-5 | | isbn_ebook | 978-94-009-5670-4 | | copyright | Springer Science+Business Media Dordrecht 1984 |
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