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Titlebook: Microorganisms as Model Systems for Studying Evolution; Robert P. Mortlock Book 1984 Springer Science+Business Media New York 1984 enzymes

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發(fā)表于 2025-3-21 18:15:59 | 只看該作者 |倒序瀏覽 |閱讀模式
書目名稱Microorganisms as Model Systems for Studying Evolution
編輯Robert P. Mortlock
視頻videohttp://file.papertrans.cn/634/633357/633357.mp4
叢書名稱Monographs in Evolutionary Biology
圖書封面Titlebook: Microorganisms as Model Systems for Studying Evolution;  Robert P. Mortlock Book 1984 Springer Science+Business Media New York 1984 enzymes
描述The microorganisms present on the earth today possess a vast range of metabolic activities and are often able to demonstrate their surprising versatility by gaining both new enzyme activities and new metabolic path- ways through mutations. It is generally assumed that the earliest micro- organisms were very limited in their metabolic abilities, but as time passed they gradually expanded their range of enzymatic activities and increased both their biosynthetic and catabolic capacity. It is also believed that these primitive microorganisms increased the amount of genetic material they possessed by duplicating their existing genes and possibly by ac- quiring genetic material from other organisms. A small group of scientists has been exploring the means by which existing microorganisms are capable of mutating to expand their bio- chemical abilities. In recent years, more attention has been focused on this type of research, sometimes called "evolution in a test tube." The recent advances in biotechnology and modern techniques of genetic trans- fer have generated new interest in the methods by which a microorgan- ism‘s metabolic activities can be improved or deliberately changed in some
出版日期Book 1984
關鍵詞enzymes; evolution; genes
版次1
doihttps://doi.org/10.1007/978-1-4684-4844-3
isbn_softcover978-1-4684-4846-7
isbn_ebook978-1-4684-4844-3
copyrightSpringer Science+Business Media New York 1984
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發(fā)表于 2025-3-21 22:00:45 | 只看該作者
https://doi.org/10.1007/978-1-4684-4844-3enzymes; evolution; genes
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Experimental Evolution of Ribitol Dehydrogenase,This project began in 1968, when the impact of amino acid sequencing and protein crystallography had revealed a flood of data with great impact on evolutionary theory. These facts allowed the following important conclusions:
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Structural Evolution of Yeast Alcohol Dehydrogenase in the Laboratory,Because our approach to the problems of molecular evolution in the laboratory is rather different from that of most of the other workers contributing to this volume, I would like to begin this review of our recent work on yeast alcohol dehydrogenase with a historical note.
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Book 1984ity by gaining both new enzyme activities and new metabolic path- ways through mutations. It is generally assumed that the earliest micro- organisms were very limited in their metabolic abilities, but as time passed they gradually expanded their range of enzymatic activities and increased both their
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Gene Recruitment for a Subunit of Isopropylmalate Isomerase, dehydrogenase (. gene product) have been purified from . and characterized (Kohlhaw ., 1969; Parson and Burns, 1970). The work described here is particularly concerned with the second leucine biosynthetic enzyme, isopropylmalate isomerase.
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