Titlebook: Microbial Toxins; P. Gopalakrishnakone (Editor-in-chief),Brad Stiles Reference work 2018 Springer Science+Business Media B.V. 2018 Drug De

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Toxins and Clinical Implicationsin the host, invasion of epithelial/macrophage cells and subsequent intercellular spread. The molecular and cellular basis of pathogenesis in melioidosis will provide a better, rational understanding toward design and development of new drugs with novel mechanisms of action.

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Epsilon Toxin: Structural and Mechanistic Insightsr the nervous excitation symptoms observed in animal enterotoxemia. At the cellular level, ETX causes a rapid swelling followed by a cell death involving necrosis. Recently, ETX has been found to induce demyelination and could be involved in demyelinating diseases like multiple sclerosis. The precise mode of action of ETX remains undetermined.

curriculum

Toxins: Efficient Biochemical Weapons for the Infectious Battleiochemical effects of these toxins..The main biochemical effects of the toxins are presented first, describing how the toxins enter target cells through binding with receptors and are finally delivered to the cytosol. In a second section, the critical targets of the toxins, during the early and late stages of the infection, are discussed.

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.e., new firm counts) and process-based indexes (i.e., comparisons of policies and regulations), the GEI is designed to profile national systems of entrepreneurship. The GEI is a construction of individual and institutional measures that integrates 31 variables from various data sources into 14 pill