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Titlebook: Microbial Surface Components and Toxins in Relation to Pathogenesis; Eliora Z. Ron,Shlomo Rottem Book 1991 Plenum Press, New York 1991 Col

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發(fā)表于 2025-3-21 19:43:27 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱Microbial Surface Components and Toxins in Relation to Pathogenesis
編輯Eliora Z. Ron,Shlomo Rottem
視頻videohttp://file.papertrans.cn/634/633047/633047.mp4
叢書名稱F.E.M.S. Symposium Series
圖書封面Titlebook: Microbial Surface Components and Toxins in Relation to Pathogenesis;  Eliora Z. Ron,Shlomo Rottem Book 1991 Plenum Press, New York 1991 Col
描述The meeting on "Microbial Surface Components and Toxins in Relation to Pathogenesis" was held on May 15-19, 1989, in the Mitzpe Rachel guesthouse of Kibbutz Ramat Rachel in Israel. Four major topics formed the basis for the meeting: adhesion and colonization; cell invasion and intracellular multipli- cation; evasion of host defenses; toxins and systemic effects. The presentations clearly show that our understanding of the pathology, pathogenesis and bacteria-host cell inter-action has greatly advanced over the last few years. The contributions to our knowledge on the biogenesis of adhesins and their molecular organization, as well as on the mechanism of adherence to infected target tissue by pathogenic bacteria, have been particularly impressive. significant progress has been made in defining the nature of pathogenic and cytotoxic factors produced by bacteria, and much has been learned about the biochemical and antigenic modifications occurring in diverse types of host cells upon infection. The discussions of poly- saccharide capsules, bacterial endotoxins and secreted toxins illustrated the challenge and the possibilities for vaccine development.
出版日期Book 1991
關(guān)鍵詞Colon; Escherichia coli; Pathogene; Pili; Toxin; biosynthesis; development; genetics; molecular aspects; prot
版次1
doihttps://doi.org/10.1007/978-1-4684-8995-8
isbn_softcover978-1-4684-8997-2
isbn_ebook978-1-4684-8995-8
copyrightPlenum Press, New York 1991
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Fimbriae of Human Enterotoxigenic , and Control of their Expressioneight, serological properties and mode of action (5, 6). The heat-stable toxin is a polypeptide of low molecular weight which is poorly antigenic (6). Two types of ST have been identified, STa or ST1 being produced by human ETEC strains. LT and ST activate adenylate cyclase and guanylate cyclase, respectively (6).
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Regulation and Function of Plasmid Encoded Virulence Determinants of ,e Ca. for prolonged growth at 37*C and they are not virulent. Although the plasmids of . and . have been subjected to rearrangements, the Ca. region, however, of the different plasmids is conserved (Fig.1) (1).
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Binding of Enterobacterial Fimbria to Proteins of Basement Membranes and Connective Tissue — A Novelhuman urine (10), and it seems that the pathogenicity of fimbriae in urinary tract infections depends both on the availability of fimbrial receptors or binding molecules in tissues and on the absence of soluble adherence inhibitors in normal human urine (reviewed in 2, 3).
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P-Fimbriae: Molecular Aspects of their Structure and their Application as Carriers of Foreign Antigecomponents composed of ? thousand protein subunits (for a review see 2). P-fimbriae specifically recognize the α -DGal(1–3) β -DGal moiety of glycolipids, which is also part of the P-blood group antigens (3, 4). Among P-fimbriae a number of different serotypes are discriminated, designated as F7–F14 (5).
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Genetics of Factors Involved in Extraintestinal , Pathogenicitye able to take up iron from the environment of the strains and they support extraintestinal . with these ions (2). Hemolysins represent protein toxins which are able to disrupt eukaryotic cells (3). Under sublethal concentrations hemolysin proteins stimulate the release of mediators of inflammation from leukocytes and mast cells (4).
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