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Titlebook: Microbial genetics applied to biotechnology :; principles and techn Venetia A. Saunders,Jon R. Saunders Book 1987 Springer-Verlag US 1987 b

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書目名稱Microbial genetics applied to biotechnology :
副標(biāo)題principles and techn
編輯Venetia A. Saunders,Jon R. Saunders
視頻videohttp://file.papertrans.cn/633/632970/632970.mp4
圖書封面Titlebook: Microbial genetics applied to biotechnology :; principles and techn Venetia A. Saunders,Jon R. Saunders Book 1987 Springer-Verlag US 1987 b
描述This book describes techniques of microbial genetics and how they may be applied to biotechnology. The text is concerned largely with the application of these techniques to microbial technology. We have therefore utilised illustrative material that is given in our own courses in applied micro- biology. The book assumes in the reader a basic knowledge of microbial will prove useful to under- genetics and industrial microbiology. We hope it graduates, postgraduates and others taking courses in applied micro- biology. We would like to thank various colleagues, including John Carter, Julian Davies, Gordon Dougan, David Hopwood, Gwyn Humphreys, Alan McCarthy, David O‘Connor, Tony Hart, Steve Oliver, Roger Pickup, Hilary Richards, Bob Rowlands, David Sherratt, Peter Strike, Richard Sykes and Liz Wellington, all of whom provided information at various stages during the writing of this book. Many thanks are also due to Linda Marsh for patiently typing the many drafts of the manuscript. 1 Introduction Natural genetic variation has always been exploited by man to improve the properties of microbial strains. Spontaneous mutations that arise in micro- bial populations and that have properties
出版日期Book 1987
關(guān)鍵詞biotechnology; genetics; microbial genetics; microbiology; microorganism
版次1
doihttps://doi.org/10.1007/978-1-4615-9796-4
isbn_ebook978-1-4615-9796-4
copyrightSpringer-Verlag US 1987
The information of publication is updating

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Genetic Manipulation,ing together and reassorting genes from different organisms. In bacteria new combinations of genes may be generated by using one of the three natural processes of gene transfer, namely . (section 2.2), . (section 2.3) or . (section 2.4). ., genetic exchange can be effected through the agency of the
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Genetic Manipulation, genetic analysis and strain improvement. Taxonomic barriers can generally be overcome, permitting the construction of hybrids that may not occur naturally. Furthermore, . techniques are more rapid and provide a much greater degree of control over the final gene product than can be achieved by most
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and , Mutagenesis,lity for microorganisms. Errors in DNA replication, misrepair of DNA damage, transposable genetic elements, environmental chemicals and radiation and the thermodynamic characteristics of nucleic acid molecules can all influence the occurrence of spontaneous (background) mutation. Induced mutations c
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Optimisation of Expression of Cloned Genes, microbial host. This not only improves the yield of such proteins from fermentations, but also assists protein recovery and other aspects of downstream processing. A variety of high-expression vectors has been constructed, principally for ., but, increasingly, for those organisms traditionally used
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