Titlebook: MicroRNAs as Tools in Biopharmaceutical Production; Niall Barron Book 2012 Springer Science+Business Media Dordrecht 2012 Bioprocessing.Ch

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MicroRNAs as Tools in Biopharmaceutical Production978-94-007-5128-6

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978-94-007-9526-6Springer Science+Business Media Dordrecht 2012

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Niall BarronBiology of microRNAs for use as tools.Implementation of these molecules to improve processes in the Biopharmceutical field.Methods to implement these molecules in the Bioprocess setting.Includes suppl

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Manipulating Levels of Specific MicroRNAs in Mammalian Cells,In this chapter, we discuss why microRNA (miRNA) manipulation is of interest to cell line engineering, and review the various approaches used to alter miRNA levels. We review the design and use of both synthetic and expressed miRNAs and miRNA inhibitors, as well as targeted insertion and deletion.

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Lyne Jossé,Lin Zhang,C Mark Smalesry material: Mankind has evolved both genetically and culturally to become a most successful and dominant species. But we are now so numerous and our technology is so p- erful that we are having major effects on the planet, its environment, and the b- sphere. For some years prophets have warned of t