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Titlebook: Methodology for Genetic Studies of Twins and Families; Michael C. Neale,Lon R. Cardon Book 1992 Springer Science+Business Media Dordrecht

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書(shū)目名稱(chēng)Methodology for Genetic Studies of Twins and Families
編輯Michael C. Neale,Lon R. Cardon
視頻videohttp://file.papertrans.cn/633/632169/632169.mp4
叢書(shū)名稱(chēng)NATO Science Series D:
圖書(shū)封面Titlebook: Methodology for Genetic Studies of Twins and Families; Michael C. Neale,Lon R. Cardon Book 1992 Springer Science+Business Media Dordrecht
描述Few would dispute the truth of the statement `People areDifferent‘, but there is much controversy over .why.. This bookauthoritatively explains the methods used to understand humanvariation, and extends them far beyond the primary `nature or nurture‘question. After chapters on basic statistics, biometrical genetics,matrix algebra and path analysis, there is a state-of-the-art accountof how to fit genetic models using the LISREL package. .The authors explain not only the assumptions of the twin method, buthow to test them. The elementary model is expanded to cover sexlimitation, sibling interaction, multivariate and longitudinal data,observer ratings, and twin-family studies. Throughout, the methods areillustrated by applications to diverse areas such as obesity, majordepression, alcohol comsumption, delinquency, allergies, and commonfears. .
出版日期Book 1992
關(guān)鍵詞alcohol; allergy; depression; genetics; methodology; obesity; sex; statistics
版次1
doihttps://doi.org/10.1007/978-94-015-8018-2
isbn_softcover978-90-481-4179-1
isbn_ebook978-94-015-8018-2Series ISSN 0258-123X
issn_series 0258-123X
copyrightSpringer Science+Business Media Dordrecht 1992
The information of publication is updating

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Univariate Analysis,n .-test version at the time of writing) in Section 8.5. This second treatment may be skipped without loss of continuity. The results of initial model-fitting to BMI data appear in Section 8.6 and two extensions to the model, the use of means and of unmatched twins, are described before drawing gene
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Power and Sample Size,the parameters in the model. This information can be used to prune the prodigious tree of possible scenarios to manageable proportions. All that is required is an understanding of the principles involved, which we aim to provide in Section 9.2. We illustrate these methods with a limited range of exa
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,Sex-limitation and G × E Interaction,tic opposite-sex twin pairs from the analysis. In the first part of this chapter (section 11.2), we outline three models for exploring sex differences in genetic and environmental effects (i.e., models for sex-limitation) and provide an example of each by analyzing twin data on body mass index (BMI)
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Michael C. Neale,Lon R. Cardon Journalismus – hielten diese Vermutung für falsch. Sie waren der Ansicht, dass die Hoechst AG nach dem erw?hnten St?rfall auch kleinste Vorf?lle an die ?ffentlichkeit weitergab und die Medien auch Vorf?lle meldeten, die sie normalerweise nie beachtet h?tten. Die Experten sahen damit – auch wenn sie
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