Titlebook: Metallomics and the Cell; Lucia Banci Book 2013 Springer Science+Business Media Dordrecht 2013 essential metal ions.homeostasis of metal i

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Control of Iron Metabolism in Bacteria,n-induced toxitiy as well as iron deficiency. This chapter describes the processes that bacteria engage in maintaining iron homeostasis. The focus is ., as this bacterium provides a well studied example. A summary of the current status of understanding of iron management at the ‘omics’ level is also presented.

內(nèi)疚

Magnesium Homeostasis in Mammalian Cells,lic stimuli. This chapter will provide an assessment of the various mechanisms controlling cellular Mg. homeostasis and transport, and the implications changes in cellular Mg. content play under physiological and pathological conditions.

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Nickel Metallomics: General Themes Guiding Nickel Homeostasis,l proteins in prokaryotic organisms with a focus on their coordination environments. Several underlying themes emerge upon review of these nickel systems, which illustrate the common principles applied by nature to shape the nickel metallome of the cell.

出血

oxidant

The Iron Metallome in Eukaryotic Organisms,yeast and mammalian cells to import iron, how this iron is brought into various organelles, and types of iron storage proteins. Regulation of these processes will be compared between yeast and mammalian cells at the transcriptional, post-transcriptional, and post-translational levels.

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Heme Uptake and Metabolism in Bacteria,tures for molecules that perform similar functions. Consequently, the aim of this chapter is to provide an overview of the structural biology of proteins and protein-protein interactions that enable Gram-positive and Gram-negative bacteria to sequester heme from the extracellular milieu, import it to the cytosol, and degrade it to mine iron.

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