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Titlebook: Mesenchymal Stem Cell Therapy; Lucas G. Chase,Mohan C. Vemuri Book 2013 Springer Science+Business Media New York 2013 Chase.MSC.Mesenchyma

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發(fā)表于 2025-3-21 16:21:37 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱Mesenchymal Stem Cell Therapy
編輯Lucas G. Chase,Mohan C. Vemuri
視頻videohttp://file.papertrans.cn/632/631011/631011.mp4
概述Includes reviews of current clinical trial results and discussions of relevant topics.Promotes a better understanding of the translation of MSCs from bench-to-bedside.Written by some of the leading re
叢書名稱Stem Cell Biology and Regenerative Medicine
圖書封面Titlebook: Mesenchymal Stem Cell Therapy; Lucas G. Chase,Mohan C. Vemuri Book 2013 Springer Science+Business Media New York 2013 Chase.MSC.Mesenchyma
描述.Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for the treatment of these diseases. Currently, more than 200 clinical trials are underway worldwide exploring the use of MSCs for the treatment of a wide range of disorders including bone, cartilage and tendon damage, myocardial infarction, graft-versus-host disease, Crohn’s disease, diabetes, multiple sclerosis, critical limb ischemia and many others..?.MSCs were first identified by Friendenstein and colleagues as an adherent stromal cell population within the bone marrow with the ability to form clonogenic colonies .in vitro. .?In regards to the basic biology associated with MSCs, there has been tremendous progress towards understanding this cell population’s phenotype and function from a range of tissue sources.? Despite enormous progress and an overall increased understanding of MSCs at the molecular and cellular level, several critical questions remain to be answered in regards to the u
出版日期Book 2013
關(guān)鍵詞Chase; MSC; Mesenchymal; Mesenchymal Stem Cell; Stem Cell; Vemuri
版次1
doihttps://doi.org/10.1007/978-1-62703-200-1
isbn_softcover978-1-62703-914-7
isbn_ebook978-1-62703-200-1Series ISSN 2196-8985 Series E-ISSN 2196-8993
issn_series 2196-8985
copyrightSpringer Science+Business Media New York 2013
The information of publication is updating

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發(fā)表于 2025-3-21 21:37:13 | 只看該作者
Mesenchymal Stromal Cells and the Repair of Cartilage Tissue,ogous chondrocytes that retain the appropriate phenotype. By contrast, the harvest and expansion of large numbers of mesenchymal stem/stromal cells (MSC) derived from tissues such as bone marrow and adipose is comparatively straightforward and has become routine in laboratories worldwide. Additional
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發(fā)表于 2025-3-22 02:07:27 | 只看該作者
Mesenchymal Stem Cells for Treatment and Prevention of Graft-Versus-Host Disease and Graft Failure is and were able to stop major hemorrhages in HSCT patients. MSCs produce hematopoietic growth factors and have been used clinically to support hematopoiesis and to treat graft failure. Future related areas of research include prospective randomized clinical trials, determining optimum cell source a
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Mesenchymal Stem Cell Therapy for Heart Disease,therapy improved left ventricular function, induced reverse remodeling, and decreased scar size. This chapter reviews the current understanding of MSC biology and mechanism of action in cardiac repair of MSC therapy for cardiac disease.
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Optimal Tissue Sources of Mesenchymal Stromal Cells for Clinical Applications,t every tissue in the body, it has been found that MSC populations retain a “memory of tissue origin” resulting in different functional abilities. This suggests that differences in MSC populations may be important for the development of future MSC therapeutic approaches for tissue and organ repair a
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