Titlebook: Meningococcal Disease; John M. Walker,Andrew J. Pollard,Martin C. J. Maid Book 2001 Humana Press 2001 infectious diseases

廚師

脆弱帶來

Serological Characterization,four useful immunoassays for serological characterization of antigens of .: whole-cell enzyme-linked immunosorbent assay (ELISA); dot blot, colony blot, and immunoblot. Serological characterization of . antigens is valuable for epidemiological studies as well as for identifying immunologically impor

北極熊

白楊魚

Nucleotide Sequencing of Antigen Genes of ,,une eradication and by promoting colonization of and adherence to epithelial cells in the nasopharynx. Surface molecules are also implicated in the patho- genicity of some meningococci by facilitating invasion of host cells, survival in the bloodstream, and resistance to phagocytosis. The antigenic

沙發(fā)

abnegate

Capsular Operons,e capsule protects meningococci from complement attack and phagocytosis and is indispensable for systemic spread of the bacteria during sepsis and meningitis (.–.). The influence of the capsule on transmission of the bacteria, colonization of the human host, entry into the bloodstream, and passage o

痛打

Armory

Representational Difference Analysis, to regulate expression of these virulence-associated genes in response to their environment. In comparison with commensals, the pathogenic phenotype can thus be seen as a consequence of both differences in gene content and gene expression. Not surprisingly, identification of these differences is a

搏斗

Managing Outbreaks, (WHO) (.). The guidance in this chapter is designed to assist in the management of the smaller-scale outbreaks or clusters, particularly in the educational setting (..). It focuses on countries, especially in Europe or North America, that are less prone to major epidemics and will normally have an

Tortuous

Global Trends in Meningococcal Disease,idemiology of meningococcal disease. Until the recent development of multi-locus sequence typing (.), multi-locus enzyme electrophoresis (abbreviated MEE or MLEE) was the only method to permit large-scale analysis of . strains causing disease in various parts of the world and to document the interco