Titlebook: Memory T Cells; Maurizio Zanetti (Professor of Medicine),Stephen P Book 2010 The Editor(s) (if applicable) and The Author(s), under exclus

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The Role of OX40 (CD134) in T-Cell Memory Generation,nals that either accentuate or limit T-cell death after activation. This chapter will focus on the TNF-receptor family member OX40, which is expressed on effector T cells and when engaged greatly enhances survival of T cells leading to increased memory T-cell generation. Targeting OX40 in vivo can a

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Longevity of T-Cell Memory following Acute Viral Infection,immunology research as well as vaccine development. Here, we review techniques that are used to assess T-cell memory including limiting dilution analysis, enzyme-linked immunospot (ELISPOT) assays, intracellular cytokine staining (ICCS) and peptide-MHC Class I tetramer staining. The durability of T-

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Principles of Memory CD8 T-Cells Generation in Relation to Protective Immunity,ing the correlation of protection against disease. In this review, we discuss our own data in the general context of current knowledge to sketch tentative working principles for the induction of protective T-cell responses by vaccination. We draw attention to quantitative and qualitative aspects of

EXUDE

Memory T Cells in Rhesus Macaques,, has demonstrated that humans and macaques share about 93% of their nucleotide sequence. Rhesus macaques have been widely used for medical research including drug testing, neurology, behavioral and cognitive science, reproduction, xenotransplantation and genetics. Because of the Rhesus macaque’s se

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