Titlebook: Membranes, Channels, and Noise; Robert S. Eisenberg,Martin Frank,Charles F. Steven Book 1984 Plenum Press, New York 1984 behavior.biology.

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ts at the membrane. The papers are revised and updated versions of presentations made at a workshop entitled "Noise Measurements as a Probe of Ionic Conductance. " As a result of discussions held at that meeting, the participants were asked to provide selected chapters designed to provide detailed d

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Synaptic Noise,ety of other biological systems. In this paper I will discuss several topics about the interpretation of noise data and its role in the study of molecular mechanisms. While specific points will be illustrated using synaptic noise studies, the reader should note the general applicability of each topic to studies of other biological noise sources.

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Analysis of Membrane Properties Using Extrinsic Noise,nel gating to interpret the data. They differ in that each experiment emphasizes a different aspect of the model for gating; but in situations where both techniques can be applied, this difference makes them complementary.

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The Information Content of Single Channel Data, seek to clarify the reasons for recording single channels, instead of measuring the mean behavior of a population of channels (whole cell recording), or the fluctuations caused by the random activity of such a population.

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Nonstationary Noise Analysis of Membrane Currents,o monitor the fluctuations in the current around its steady mean value. In practice, an experiment of this kind is often not possible because of properties of the channels themselves. Acetylcholine-receptor channels, for example, show a desensitization process in which the agonist-induced membrane c

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