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Titlebook: Membrane Transporters as Drug Targets; Gordon L. Amidon,Wolfgang Sadée Book 2002 Springer Science+Business Media New York 2002 Amino acid.

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發(fā)表于 2025-3-21 20:02:51 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱Membrane Transporters as Drug Targets
編輯Gordon L. Amidon,Wolfgang Sadée
視頻videohttp://file.papertrans.cn/631/630415/630415.mp4
叢書名稱Pharmaceutical Biotechnology
圖書封面Titlebook: Membrane Transporters as Drug Targets;  Gordon L. Amidon,Wolfgang Sadée Book 2002 Springer Science+Business Media New York 2002 Amino acid.
描述Because progress in the field of transporters has beenextraordinary, this volume will focus on recent advances in ourunderstanding of the structure, function, physiology, and molecularbiology of membrane transporters. There will be an emphasis ontransporters as molecular targets for drug delivery and disposition inthe body.
出版日期Book 2002
關(guān)鍵詞Amino acid; Antigen; Glucose; Nucleoside; biology; drug; drug delivery; ion transport; membrane transport; mo
版次1
doihttps://doi.org/10.1007/b112928
isbn_softcover978-1-4757-8631-6
isbn_ebook978-0-306-46812-4Series ISSN 1078-0467
issn_series 1078-0467
copyrightSpringer Science+Business Media New York 2002
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Molecular and Functional Characteristics of Cloned Human Organic Cation Transporters,t will be years and perhaps several more decades before all of these transporters are cloned and characterized. We have made a good start and there will be years of exciting work and discovery in the organic cation transport field in the future.
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發(fā)表于 2025-3-22 09:19:59 | 只看該作者
Organic Anion Transporters,ers probably have physiologically crucial roles, manipulation of drug disposition by utilization of these transporters is expected to be useful for regulating the pharmacokinetics of anionic drugs not only in intestinal absorption and renal and hepatic elimination, but also in distribution into pharmacological target tissues.
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Drug Transport and Targeting,tinal transporters are located in the brush border membrane as well as basolateral membrane. Each transporter exhibits its own substrate specificity, and some have broader specificities than others. In addition, the distribution and characteristics of the intestinal transporters exhibit regional dif
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發(fā)表于 2025-3-23 03:35:47 | 只看該作者
Cationic Amino Acid Transporters (CATs),oday, we know that there are at least three different CAT isoforms that mediate y. activity and the family might be growing. In addition, transport systems for cationic amino acids other than y + have been described and proteins that induce the respective transport activities have been identified. C
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Electrophysiological Analysis of Renal Na+-Coupled Divalent Anion Transporters,tics provides essential information for both model generation and identification of partial reactions in the transport cycle which play a critical role in determining kinetic parameters. Furthermore, the voltage dependence of the apparent affinity constants obtained from the steady state serves to e
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