Titlebook: Membrane Toxicity; Morton W. Miller,Adil E. Shamoo Book 1977 The Editor(s) (if applicable) and The Author(s), under exclusive license to S

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Tikvah Alper D.Sc.ent and function of immune responses. With the recent advances in cellular and molecular immunology, strategies are now being developed that effectively and safely augment antitumor responses. These advances have enabled the characterization of so-called . (TAA) which can function as targets for the

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Effect of P-Chloromercuribenzoate (pCMB), Ouabain and 4-Acetamido-4′ISO-Thiocyamatostilbene-2,2′-Disero net flux concentration (electrochemical potential) differences which are proportional to the respective active transport rates of H. Cglycodiazine), D-glucose (α-methyl-D-glycoside), L-histidine, inorganic phosphate and calcium ions. 3. Transtubular and transcellular electrical potential differe

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Heavy Metals and Membrane Functions of an Alveolar Epitheliumhibited a transmural electrical p.d. of 19 mV (pleura positive), a resistance of 700 ohm cm. and a short-circuit current (I.) of 27 μa/cm.. I. reflected active Cl. secretion into the lumen by a transport mechanism located at the luminal border of the alveolar epithelial cell layer. Other halides and

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The Localization of Ion-Selective Pumps and Paths in the Plasma Membranes of Turtle Bladdersitions. This behavior mimics that of a parallel network of ion-selective, electrically-conductive paths and pumps in each membrane, — a picture consistent with recent evidence along three independent lines. (1) The potential response to increases in mucosal Na concentration indicates that the Na con

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Liver Endoplasmic Reticulum: Target Site of Halocarbon Metabolites reticulum. First, there is dispersion of the ergastoplasm, then vacuolization and degranulation of the rough endoplasmic reticulum with concomitant retraction of the smooth endoplasmic reticulum into tightly clumped tubular aggregates. In addition, membranes in these tubular aggregates seem to unde

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Mechanisms by Which Small Molecules Alter Ionic Permeability Through Lipid Bilayer Membranesy which such molecules may act on membrane permeability are examined here in light of the rather precise understanding of the mechanisms by which ionic permeability is induced and altered in lipid bilayer membranes. In particular, the influence of specific changes in membrane composition on the kine

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Effects of Neomycin on Polyphosphoinositides in Inner Ear Tissues and Monomolecular Filmslinositol diphosphate was measured in inner ear tissues. Concentrations of neomycin which decreased the electrophysiological response of the cochlea to sound stimulation also decreased labeling of phosphatidylinositol diphosphate. . experiments with brain tissues and polyphosphoinositide extracts in