Titlebook: Membrane Dynamics and Calcium Signaling; Joachim Krebs Book 2017 Springer International Publishing AG, part of Springer Nature 2017 calciu

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Structure-Function Relationship of the SERCA Pump and Its Regulation by Phospholamban and Sarcolipinnd relaxation of cardiac muscle cells are regulated by the cyclic movement of calcium primarily between the extracellular space, the cytoplasm and the sarcoplasmic reticulum (SR). The rapid removal of calcium from the cytosol is primarily facilitated by the sarco(endo)plasmic reticulum calcium ATPas

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Structural Details of the Ryanodine Receptor Calcium Release Channel and Its Gating Mechanismdiac and skeletal muscle cells. In addition, they are expressed in other cell types where their function is less well understood. Hundreds of mutations in the different isoforms of RyR have been associated with inherited myopathies and cardiac arrhythmia disorders. The structure of these important d

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Beyond Intracellular Signaling: The Ins and Outs of Second Messengers Microdomainsional components: for example, most of the genetic material is surrounded by a highly specific membrane structure (the nuclear membrane), continuous with, yet largely different from, the endoplasmic reticulum (ER); oxidative phosphorylation is carried out by organelles enclosed by a double membrane,

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