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Titlebook: Mechanisms of Physical and Emotional Stress; George P. Chrousos,D. Lynn Loriaux,Philip W. Gold Book 1988 The Editor(s) (if applicable) and

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書目名稱Mechanisms of Physical and Emotional Stress
編輯George P. Chrousos,D. Lynn Loriaux,Philip W. Gold
視頻videohttp://file.papertrans.cn/629/628752/628752.mp4
叢書名稱Advances in Experimental Medicine and Biology
圖書封面Titlebook: Mechanisms of Physical and Emotional Stress;  George P. Chrousos,D. Lynn Loriaux,Philip W. Gold Book 1988 The Editor(s) (if applicable) and
描述It has been over 50 years since Hans Selye formulated his concept of stress. This came after the isolation of epinephrine and norepinephrine and after the sympathetic system was associated with Walter Cannon‘s "fight or flight" response. The intervening years have witnessed a number of dis- coveries that have furthered our understanding of the mechanisms of the stress response. The isolation, identification and manufacture of gluco- corticoids, the identification and synthesis of ACTH and vasopressin, and the demonstration of hypothalamic regulation of ACTH secretion were pivotal discoveries. The recent identification and synthesis of CRR by Willie Vale and his colleagues gave new impetus to stress research. Several new concepts of stress have developed as a result of advances in bench research. These include the concept of an integrated "stress sys- tem", the realization that there are bi-directional effects between stress and the immune system, the suggestion that a number of common psychiatric disorders represent dysregulation of systems responding to stress, and the epidemiologic association of stress with the major scourges of humanity.
出版日期Book 1988
關(guān)鍵詞CNS; behavior; biology; pharmacology; regulation; reproduction
版次1
doihttps://doi.org/10.1007/978-1-4899-2064-5
isbn_softcover978-1-4899-2066-9
isbn_ebook978-1-4899-2064-5Series ISSN 0065-2598 Series E-ISSN 2214-8019
issn_series 0065-2598
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines
The information of publication is updating

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978-1-4899-2066-9The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines
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CRH Effects on Central Noradrenergic Neurons: Relationship to Stressotential function is to modify behavior or autonomie acitivity. It should alter activity of neurons in these target regions, and a mechanism should exist to translate CRH electrophysiological effects to appropriate behaviors or autonomic responses that are normally observed in the stress response. M
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Corticotropin Releasing Factor Receptors: Characterization and Actions in the Anterior Pituitary Glas greatly aided our understanding of the physiological actions of CRF in these tissues. The most common ligand used for CRF receptor studies is the radioiodinated ovine CRF derivative, Tyr-oCRF; similar receptor properties have been described using radioiodinated [NLeu., Tyr.]oCRF (5). Analogues of
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