Titlebook: Mechanisms of Lymphocyte Activation and Immune Regulation VIII; Autoimmunity 2000 an Sudhir Gupta Book 2001 The Editor(s) (if applicable) a

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Multiple Sclerosis and Gene Expression Profiling brains, as well as four brains with Huntington’s Disease, and four brains with Parkinson’s Disease.. Using a 6800 gene Affymetrix microarray, large increases in transcription of genes encoding key components of the immune response have been seen..

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Cytokine Blockade in Rheumatoid Arthritis review the rationale for anti TNFa therapy, the current status of therapy and focus on the regulation of TNFa production in rheumatoid synovium. New approaches to studying TNF regulation in RA and of elucidating the controversial role of T cells in this complex disease will be described.

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https://doi.org/10.1007/978-1-4615-1243-1T cell; autoimmune disease; autoimmunity; biochemistry; biology; cell; cell biology; cytokine; diseases; gene

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Peripheral Tolerance and Organ Specific Autoimmunityd receptor-deletion whereby immature B but not T cells change their receptors when confronted with antigen, perhaps because the antigen keeps the rearrangement process ongoing whereby already productive genes are deleted and new ones are being generated. Thus we have clonal or cellular deletion as w