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Titlebook: Mechanisms of Lymphocyte Activation and Immune Regulation VI; Cell Cycle and Progr Sudhir Gupta,J. John Cohen Book 1996 The Editor(s) (if a

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書(shū)目名稱(chēng)Mechanisms of Lymphocyte Activation and Immune Regulation VI
副標(biāo)題Cell Cycle and Progr
編輯Sudhir Gupta,J. John Cohen
視頻videohttp://file.papertrans.cn/629/628741/628741.mp4
叢書(shū)名稱(chēng)Advances in Experimental Medicine and Biology
圖書(shū)封面Titlebook: Mechanisms of Lymphocyte Activation and Immune Regulation VI; Cell Cycle and Progr Sudhir Gupta,J. John Cohen Book 1996 The Editor(s) (if a
描述Since programmed cell death was first described in insects in 1964 and apoptosis was described in 1972, rapid progress has been made in understanding the basic mechanisms and genes regulating programmed cell death and apoptosis. In addition, defects in various genes regulating programmed cell death have been delineated in several experimental models of human diseases. This volume surveys various aspects of these rapidly developing areas of research in programmed cell death/apoptosis. This volume should be of interest to basic immunologists and molecular biologists. The volume begins with a historical perspective of cell death. The remainder of the volume is divided into four different parts. Part I deals with the signaling pathways in apoptosis, including cell cycle control of apoptosis, role of ceramide in apoptosis, role of antibody signaling, and biochemical regulation of apoptosis. The mechanisms for recognition of apoptotic lymphocytes by macrophages are also reviewed. Part II examines the role of various genes that regulate apoptosis, including the role ofFas, FasL, and other TNF family members in apoptosis and homeostatic regulation of immune response. Recently described spl
出版日期Book 1996
關(guān)鍵詞T cell; Thymus; apoptosis; diseases; insects; lymphocytes; macrophages; programmed cell death; proteins; viru
版次1
doihttps://doi.org/10.1007/978-1-4899-0274-0
isbn_softcover978-1-4899-0276-4
isbn_ebook978-1-4899-0274-0Series ISSN 0065-2598 Series E-ISSN 2214-8019
issn_series 0065-2598
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines
The information of publication is updating

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Signals for Survival and Apoptosis in Normal and Neoplastic B Lymphocytestly the behaviour of cell lines dervied from biopsy material with that of the normal counterparts. Here we describe some of our findings in the two systems with regard to signals regulating survival and apoptosis.
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Role of Antibody Signaling in Inducing Tumor Dormancynts, are frequent indicating that the antibody (Ab) was particularly effective in inducing dormancy in cells bearing the corresponding idiotope but that hypermutation of V. and V. genes eventually allow some tumor cells from the original clone to escape..
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發(fā)表于 2025-3-22 16:48:09 | 只看該作者
Fas-Mediated Apoptosisromosomal DNA into oligomers of 180 bp. Cellular proliferation and differentiation are mediated by a family of proteins called cytokines. Our studies on the Fas ligand and Fas have indicated that apoptosis is also mediated by a cytokine and its receptor in some cases. Here, I summarize the current status of the Fas death factor system.
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發(fā)表于 2025-3-22 19:24:32 | 只看該作者
Apoptosis and Its Regulation of mitosis, regardless of their location in the body or their ultimate destiny. And these cells die by either of two processes, roughly equivalent to accidents and natural causes. Just as a pathologist will determine cause of death by examining the body, we distinguish the two forms of cell death by morphology..
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發(fā)表于 2025-3-22 23:16:12 | 只看該作者
Cytotoxic Lymphocyte Killing Enters the Ice Age to engage the same cellular machinery that is responsible for the destruction of the cell from within. Thus, although the proximal signalling events that can result in apoptosis can vary from one stimulus to another, it is likely that these signals all converge at some point on a common set of effector molecules which we will call ‘.’.
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發(fā)表于 2025-3-23 01:43:05 | 只看該作者
The Role of FasL and TNF in the Homeostatic Regulation of Immune Responsesad indicated that ligation of this receptor in mAb resulted in the death of certain transformed cell lines via a process known as apoptosis. This process is characterized by cytoplasmic condensation, plasma membrane convolution, nuclear condensation and DNA fragmentation..
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