Titlebook: Mechanisms of Lymphocyte Activation and Immune Regulation III; Developmental Biolog Sudhir Gupta,William E. Paul,Ellen V. Rothenberg Book 1

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書目名稱Mechanisms of Lymphocyte Activation and Immune Regulation III讀者反饋學(xué)科排名

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Kinetics of Negative and Positive Selection in the Thymusfic peptide. Different tolerogens delete CD4.8. thymocytes earlier or later during their lifespan and negative selection can occur prior to positive selection. The specificity of the . T cell receptor for either class I or class II thymic MHC molecules determines the CD4.8. and CD4.8. phenotype of mature T cells.

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First Wave Fetal Thymocytes Expressing V3Jγ1Cγ1-Vδ1Jδ2Cδ T Cell Receptors are not Required For , T Cr the rearrangement, expression and maturation of the . TcR repertoire. We are currently analyzing a series of γ. transgenic mice to determine whether other restricted populations of γ.-bearing T cells are involved in specific aspects of immune development or function.

浪蕩子

T Cells in Murine Epithelia: Origin, Repertoire, and Functionmprise the bulk, if not the entirety, of the T cells. There is a tight correlation between Vγ gene usage and epithelial localization as well as differences in the potential TCR repertoire in the different epithelia, two features which raise important questions as to the origin, homing, selection, and function of these cells.

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Monoclonal Antibodies Against T Cell Receptor/CD3 Complex Induce Cell Death of Th1 Clones in the Abses signals. Numerous studies indicate that such recognition can result in a variety of consequences, including cell proliferation, cytokine production, cell death,. and clonal anergy.. However, the mechanisms by which the outcomes of T cell recognition is determined are largely unknown.

曲解

Multiple Mechanisms of T Cell Tolerance to Mls-latolerance. Three mechanisms have been proposed for maintaining self tolerance-clonal deletion, or elimination of self-reactive clones, clonal anergy, or functional inactivation of self-reactive clones, and suppression, or negative regulation of self-reactive clones.

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0065-2598 and in part on the analysis of the behavior of long term T-cell lines. This has led to the realization that both clonal deletion and clonal anergy may play cri978-1-4684-5945-6978-1-4684-5943-2Series ISSN 0065-2598 Series E-ISSN 2214-8019