Titlebook: Mechanisms of DNA Damage Recognition in Mammalian Cells; Hanspeter Naegeli Book 1997 Springer Science+Business Media Dordrecht 1997 DNA.DN

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書目名稱Mechanisms of DNA Damage Recognition in Mammalian Cells影響因子(影響力)




書目名稱Mechanisms of DNA Damage Recognition in Mammalian Cells影響因子(影響力)學(xué)科排名




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書目名稱Mechanisms of DNA Damage Recognition in Mammalian Cells讀者反饋學(xué)科排名

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Molecular Determinants of Damage Recognition by Mammalian Nucleotide Excision Repair,re 7.1, this hypothesis was prompted by the observation that many base lesions alter the helical parameters of DNA by inducing kinks,. bends. or localized unwinding,. suggesting that damage-induced conformational distortion may constitute an important determinant of recognition by the nucleotide excision repair system.

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Intragenomic Hierarchies of DNA Damage Recognition,or suppress photoproduct formation within active genes.. Similarly, the distribution of DNA adducts formed by chemical reagents is dependent on the protein environment and the nucleotide sequence context..

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Springer Science+Business Media Dordrecht 1997

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Mechanisms of DNA Damage Recognition in Mammalian Cells978-1-4684-6468-9Series ISSN 1431-0414

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1431-0414 Overview: 978-1-4684-6468-9Series ISSN 1431-0414

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https://doi.org/10.1007/978-1-4684-6468-9DNA; DNA damage; Nucleotide; enzyme; reactions; replication; stability; structure; toxicology

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DNA Structure: Inherent Instability and Genotoxic Reactions,The principal goal of this chapter is to provide examples of biologically significant lesions in DNA that are (1) chemically and structurally well characterized and (2) serve as experimental models to understand how DNA damage is recognized in mammalian chromosomes.

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