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Titlebook: Mechanisms of Carcinogenesis; Elizabeth K. Weisburger Book 1989 Kluwer Academic Publishers 1989 Mamma.Tumor.cancer.carcinogenesis.carcinom

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,The Quantum Theory of Carcinogenesis — A Short Review,ned in the DNA of all cells. This will be effective, however, only when those proteins are removed which block the transcription of this cancerous information. Once these nucleoproteins have been released, proteins are produced according to the code of the generally blocked gene in the DNA. The func
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Amplification of the Oncogene N-, as a Correlate to Advanced Stage in Human Neuroblastomas,rsible qualitative change in one or more of the characters of neoplastic cells” (15). Much discussion has focused on the nature of these changes and, as a general assessment, they seem to be genetic and epigenetic. While it has been difficult to define exactly epi-genetic mechanisms related to tumor
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Potential Roles of Activated Proto-Oncogenes in Malignant Progression,e transformation in non-tumorigenic NIH 3T3 cells, initially challenged long-standing concepts as to the genetic basis for cancer. These results suggested that discrete genes, termed proto-oncogenes, were associated with development of malignancy. The possibility that one such gene could induce the
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Oncogene Products as Potential Therapeutic Targets for Control of Established Metastatic Disease,4, this volume). The potential of elucidating the molecular mechanisms operative in neoplastic transformation has generated widespread excitement and research interest within the scientific community, particularly among cancer biologists. A large component of research performed in this area has been
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