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Negative Selection of Self-reactive B Lymphocytes Involves Complement For example, mice bearing targeted disruption of molecules involved in regulation of BCR signaling such as CD22, SHP-1 (Cyster et al. 1995), CD45 (Cyster et al. 1996) or Lyn (Cornall et al. 1998) have altered negative selection of self-reactive B cells in the sHEL/HEL-Ig double tg model. Alternativ

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Cross-talk Between CD44 and c-Met in B cellseceptor ligation. Stimulation of c-Met with HGF/SF, which is produced at high levels by tonsillar stromal cells and FDC, leads to enhanced integrin-mediated adhesion of B cells to fibronectin and VCAM-1 [22].

META

Role of Complement Receptors CD21/CD35 in B Lymphocyte Activation and Survivalplement and is particularly important in recognition of protein antigens in addition to carbohydrate. For the purposes of this review, the enhancing effect of complement is most probably mediated by natural IgM, as deficiency in secretory IgM results in an impaired B cell response to suboptimal dose

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Chemokines and B-cell Homing to Folliclesin humans (Birkenbach et al. 1993; Dobner et al. 1992). To track expression of the mouse receptors, the amino-terminal ectodomains were expressed as GST fusion proteins and used to immunize rabbits. An antiserum against BLR1 was isolated and affinity purified using the same BLR1 fragment expressed a

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R. A. Manz,G. Cassese,A. Thiel,A. Radbruch hopes that the young scientists of the next generation will be enthusiastically inspired by this book and will develop the field of organic semiconductors even further..978-981-99-1239-1978-981-99-1237-7Series ISSN 1386-3290

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C. Schaniel,F. Sallusto,P. Sideras,F. Melchers,A. G. Rolinkoducts and systems. The chapters in this book may further give impetus to explore new avenues leading towards multidisciplinary research discussions associatedwith the resilience and sustainability of the existing systems..978-981-99-1523-1978-981-99-1521-7Series ISSN 2731-4049 Series E-ISSN 2731-4057

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