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Titlebook: Mechanism of Action; David Gottlieb (Professor of Plant Pathology),Paul Book 1967 Springer-Verlag Berlin · Heidelberg 1967 Chloramphenicol

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發(fā)表于 2025-3-21 19:31:37 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書目名稱Mechanism of Action
編輯David Gottlieb (Professor of Plant Pathology),Paul
視頻videohttp://file.papertrans.cn/629/628640/628640.mp4
叢書名稱Antibiotics
圖書封面Titlebook: Mechanism of Action;  David Gottlieb (Professor of Plant Pathology),Paul Book 1967 Springer-Verlag Berlin · Heidelberg 1967 Chloramphenicol
描述The idea for publishing these books on the mechanism of action and on the biosynthesis of antibiotics was born of frustration in our attempts to keep abreast of the literature. Gone were the years when we were able to keep a biblio- graphy on antibiotics and feel confident that we could find everything that was being published on this subject. These fields of investigation were moving for- ward so rapidly and were encompassing so wide a range of specialized areas in microbiology and chemistry that it was almost impossible to keep abreast of developments. In our naivete and enthusiasm, however, we were unaware that we were toying with an idea that might enmesh us, that we were creating an entity with a life of its own, that we were letting loose a Golom who instead of being our servant would be our master. That we set up ideals for these books is obvious; they would be current guides to developments and information in the areas of mechanism of action and bio- synthesis of antibiotics. For almost every subject, we wished to enlist the aid of an investigator who himself had played a part in determining the nature of the phenomena that were being discussed. One concept for the books wa
出版日期Book 1967
關(guān)鍵詞Chloramphenicol; Tetracycline; antibiotics; bacteria; biology; biosynthesis; cell; chemistry; microbiology; p
版次1
doihttps://doi.org/10.1007/978-3-642-46051-7
isbn_softcover978-3-642-46053-1
isbn_ebook978-3-642-46051-7
copyrightSpringer-Verlag Berlin · Heidelberg 1967
The information of publication is updating

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發(fā)表于 2025-3-21 20:33:02 | 只看該作者
Pyocyanine,ase. Later investigations, however, showed that several factors were present, none of which had enzymatic activity, and that the major active principle was pyocyanine. The isolation and chemical nature of pyocyanine has been described by S. (1941) and the structure was elucidated by W. and S. (1924, 1929) and H. (1938).
板凳
發(fā)表于 2025-3-22 04:10:55 | 只看該作者
Pluramycin,) observed that a macromolecular antitumor substance (molecular weight 30, 000–60, 000) is also produced by the same organism. It consists of a pluramycin-like prosthetic group and a glycoprotein, and is designated plurallin.
地板
發(fā)表于 2025-3-22 07:16:30 | 只看該作者
Daunomycin and Related Antibiotics, Daunomycin is closely related to the anthracyclines. Following B. suggestion (4963), those antibiotics that contained a tetrahydrotetracenquinone chromophore linked to a sugar should all be included in the anthracycline group. The chromophores of such antibiotics have different substituents on the nucleus (Fig. 1 and Table 1).
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s to keep abreast of the literature. Gone were the years when we were able to keep a biblio- graphy on antibiotics and feel confident that we could find everything that was being published on this subject. These fields of investigation were moving for- ward so rapidly and were encompassing so wide a
6#
發(fā)表于 2025-3-22 13:30:37 | 只看該作者
Penicillins and Cephalosporins, effects may be dominant and of the greatest significance while a biochemically minded individual will wish to know the nature of specific metabolic changes; a clinician interested in infectious diseases wishes to know what events are observable in the host and how these relate to the probable success or failure of his therapy.
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發(fā)表于 2025-3-23 03:19:39 | 只看該作者
Griseofulvin,y of “curling factor” with griseofulvin was determined chemically by GROVE and MCGOWAN (1947), and biologically by B... (1949). Subsequent studies have demonstrated that . and . also produce the antibiotic (B..., 1949, 1955). The griseofulvin analogs, bromogriseofulvin and dechlorogriseofulvin have also been isolated from fungi (M., 1951, 1954).
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發(fā)表于 2025-3-23 08:56:01 | 只看該作者
Chromomycin, Olivomycin and Mithramycin,tics is similar, but not identical; there are also some differences in the toxicity and pharmacology of these products, which have been compared in a recent review (G., 1965). Biochemical mechanisms of action of these antibiotics have much in common.
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