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Titlebook: Matrix Pathobiology and Angiogenesis; Evangelia Papadimitriou,Constantinos M. Mikelis Book 2023 The Editor(s) (if applicable) and The Auth

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樓主: ARSON
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發(fā)表于 2025-3-25 05:23:24 | 只看該作者
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Kruppel-Like Factor 2 and Matrix Metalloproteinases in the Context of Vasculature, response to angiogenic and inflammatory stimuli. MMPs are endoproteases that play a large part in the degradation of various components of the extracellular matrix (ECM) and tissue remodeling. They are essential mediators of inflammation, angiogenesis, and vascular remodeling. KLF2 is a transcripti
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發(fā)表于 2025-3-25 19:10:04 | 只看該作者
Extracellular Matrix Remodeling Enzymes as Targets for Natural Antiangiogenic Compounds,and antiangiogenic signals. Although physiological angiogenesis occurs in some context, such as embryogenesis or wound healing, it is a very restricted process in adults. A deregulated angiogenesis?is associated to several pathologies such as cancer, arthritis, or age-related macular degeneration. F
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發(fā)表于 2025-3-25 23:40:13 | 只看該作者
,Cell–Extracellular Matrix Adhesions in Vascular Endothelium,chanical forces, enables multi-organ communication by circulating hormones and biochemical cues, and provides a gateway for immune surveillance. Genetic deletion of essential components of blood vessel formation leads to embryonic lethality, which emphasises the importance of this system. Blood vess
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發(fā)表于 2025-3-26 02:00:37 | 只看該作者
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發(fā)表于 2025-3-26 07:47:03 | 只看該作者
Leading Roles of Heparan Sulfate in Angiogenesis and Cancer,AGs are present in tissues as proteoglycans. HS proteoglycans (HSPGs) are found at the cell surface and in the extracellular matrix, where they interact with a plethora of ligands. HSPGs play important roles in cancer initiation and progression, interacting with numerous signaling pathways that affe
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發(fā)表于 2025-3-26 14:28:40 | 只看該作者
Lymphatic Mechanoregulation in Development and Disease,ese interactions confer extracellular mechanical information, such as fluid shear stress, cellular stretch, and matrix stiffness, on the endothelium and are subsequently translated into intracellular biological responses. The impact of changes in fluid shear stress has been extensively studied in bo
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發(fā)表于 2025-3-26 17:58:40 | 只看該作者
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