Titlebook: Mass Spectrometry-Based Proteomics; Kris Gevaert Book 2023 The Editor(s) (if applicable) and The Author(s), under exclusive license to Spr

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A Robust and Clinically Applicable Sample Preparation Protocol for Urinary Extracellular Vesicle Isto-use uEV isolation protocol is needed that is compatible with proteomics. Here, we provide a detailed description of a quick and clinical applicable uEV isolation protocol. We focus on the isolation procedure and subsequent in-depth proteome characterization using LC–MS/MS-based proteomics. As an

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Mass Spectrometry-Based Analysis of Histone Posttranslational Modifications from Laser Microdissectout the implication of epigenetics in a multitude of physiological and pathological processes. Mass spectrometry (MS) has emerged as the most accurate and versatile tool to detect and quantify histone PTMs and has also been applied to clinical specimens, thanks to protocols developed during the past

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Probing Antibody Structures by Hydrogen/Deuterium Exchange Mass Spectrometry,a protein structure. It has been widely recognized as an indispensable tool and already approved by several regulatory agencies as a structural technique for the validation of protein biopharmaceuticals, including antibody-based drugs. Antibodies are of a key importance in life and medical sciences

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Delphi Van Haver,Amélie Dendooven,Francis Impensm Fernsprechbereich benutzten Tr?gerfrequenztechnik als ein Beispiel für ein hierarchisches Konzept zur Mehrfachausnutzung von übertragungskan?len. Aufgrund der verh?ltnism??ig geringen qualitativen Ansprüche an die Sprachübertragung wird unter dem Gesichtspunkt einer optimalen Bandbreite-Effizienz

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Leyla A. Erozenci,Irene V. Bijnsdorp,Sander R. Piersma,Connie R. Jimenezd der Fall unvollst?ndig ged?mpfter benachbarter Sendesignale untersucht, was z.B. bei der Rundfunkübertragung infolge sehr dicht angeordneter Sendefrequenzen ein gro?es Problem darstellt. Die Auswirkungen auf das demodulierte Signal werden für Amplituden- und Frequenzmodulation analysiert. Additive