Titlebook: Manual of Cardio-oncology; Cardiovascular Care Chiara Lestuzzi,Stefano Oliva,Francesco Ferraù Book 2017 Springer International Publishing

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The Pharmacologist’s Point of View: Mechanisms of Cardiotoxicityed in the reduction of recurrences. However, many anticancer agents, while successuful in their anti-tumor activities, are often associated with side effects affecting the cardiovascular compartment, leading to an increase in morbidity and mortality. Here we will discuss the cellular and molecular a

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Cardiotoxicity: Hypertensionbout 20% in the United States in the last years Anyway, extensive cancer research has demonstrated that the use of new biologic drugs might be indicated in patients with neoplasia, in particular in the setting of metastatic cancer.Renal surgery has represented the first line of treatment for renal c

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Radiotherapy: Clinical Aspects and Cardiotoxicityive stress through free radical production and results in recruitment of matrix metalloproteinases and pro-inflammatory mediators. These changes may lead to acute toxicity (evident during or shortly after radiotherapy) and start a chronic process leading to delayed dysfunction that is evident severa

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Cardiotoxicity in the Elderlyeading cause of death. Actually, cancer cases reported over the world have doubled in the past 25 years and could even triple by 2030. In fact, the elderly population is rapidly increasing, in Europe 15 % of the population is elderly, and 55 % of cancers are in this group of age [1, 2]. Therefore, a

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Arrhythmias and Electrolyte Imbalances as Consequences of CancerBoth arrhythmias and electrolyte imbalances are rather frequent consequences of cancer itself and of cancer treatments (and their side effects). Arrhythmias may be also a consequence of electrolyte imbalance.

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Cardiotoxicity: Cardiac IschemiaSeveral antineoplastic treatments have been associated with cardiac ischemia as a side effect. For most of them, however, large studies are lacking and the association is weak.