Titlebook: Managing BRCA Mutation Carriers; Anees B. Chagpar Book 2017 Springer International Publishing AG 2017 Pathology of BCRA.DNA damage repair.

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書目名稱Managing BRCA Mutation Carriers影響因子(影響力)




書目名稱Managing BRCA Mutation Carriers影響因子(影響力)學科排名




書目名稱Managing BRCA Mutation Carriers網(wǎng)絡公開度




書目名稱Managing BRCA Mutation Carriers網(wǎng)絡公開度學科排名




書目名稱Managing BRCA Mutation Carriers被引頻次




書目名稱Managing BRCA Mutation Carriers被引頻次學科排名




書目名稱Managing BRCA Mutation Carriers年度引用




書目名稱Managing BRCA Mutation Carriers年度引用學科排名




書目名稱Managing BRCA Mutation Carriers讀者反饋




書目名稱Managing BRCA Mutation Carriers讀者反饋學科排名

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s.Written by experts in their fields.Includes supplementary As there are a number of nuances in terms of how to manage mutation carriers (both with and without a concomitant diagnosis of breast cancer), this text provides a comprehensive, state-of-the art review of this field. It represents a valuab

Forsake

Risk Assessment for Breast Cancer,ic testing; and most important, ensure that the patient follows through. With each of these steps, a certain proportion of patients is lost. Mary-Claire King, the human geneticist who discovered the . mutation, once stated that “to identify a woman as a carrier only after she develops cancer is a failure of cancer prevention.” We can do better.

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FLEET

Risk Assessment for Breast Cancer,fected . mutation carriers before they develop breast cancer can reduce their risk and increase survival through increased intensity and frequency of screening, prophylactic surgery, and use of chemopreventive agents. Although the tools for genetic testing have been available for the past 20?years,

Indolent

Genetic Evaluation for Women at Increased Risk,family history of cancer that may be associated with a hereditary cancer predisposition. The collection of an accurate, cancer-focused family history is the foundation of this risk assessment. Professional organizations have created guidelines outlining when patients should be referred to a provider

吹牛大王

Imaging Screening and Surveillance,sitivity of screening MRI in this population is 90–95%, more than twice that of mammography, with a specificity of over 90% after the first round of screening. Ten-year breast cancer-free survival, though likely somewhat lower than that with risk-reducing mastectomy, is at least 90%. The incremental

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Risk-Reducing Surgery for , Genetic Mutation Carriers,y has been shown to reduce the risk of breast cancer by 90% or more among high-risk women including . mutation carriers. The decision to undergo prophylactic surgery is a choice that patients make, in conjunction with their multidisciplinary healthcare team which often includes genetic counselors, s