Titlebook: Management of Breast Cancer in Older Women; Malcolm W. Reed,Riccardo A. Audisio Book 20101st edition Springer-Verlag London Limited 2010 T

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Tumor Biology and Pathologymen aged 65 years or more, a proportion which is likely to grow because of increased life expectancy and therefore increased proportion of elderly subjects in the general population. The 10-year probability of developing invasive breast cancer increases from less than 1.5% at age 40 to about 3% at a

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Impact of the Physiological Effects of Aging on the Pharmacokinetics and Pharmacodynamics of Systemi changes and the impact on pharmacokinetics (PKs) and pharmacodynamics (PDs) of systemic anticancer treatment are linked mechanistically to altered drug handling and altered physiological reserve. The risk of death does increase with chronological age, which is consistent with a progressive and inde

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Impact of Hormone Replacement Therapy on Breast Cancerbed. The use of HRT for the treatment of the symptoms of menopause is widespread and well recognized. However, the exposure to exogenous hormones in postmenopausal women and the subsequent risk of cancer in general, and breast cancer in particular, have been of interest..The reproductive life of wom

Certainty

Experiences of a Multidisciplinary Elderly Breast Cancer Clinic: Using the Right Specialists, in theials have included older patients, particularly if they are frail. Evidence for treatment benefit, obtained from trials on a younger patient population, cannot directly apply to frail patients, as such application would under-estimate risk. This means, for example, that a frail patient may not benef

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Primary Endocrine Therapy for the Treatment of Early Breast Cancer in Older Womenrine therapy, chemotherapy, and Trastuzumab. Primary endocrine therapy (PET), by comparison, is the use of an antiestrogen as the sole method of treatment for early stage, operable, estrogen receptor (ER) positive breast cancer in women who may be less able to tolerate standard therapy..PET is widel

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Peroperative Radiotherapye is growing that after BCT, most recurrences appear at or near the lumpectomy cavity. Therefore, several leading institutions are investigating the possibility to limit the peroperative treatment only to the volume of breast surrounding the original tumor site. Reducing the treated volume can also