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Titlebook: Mammalian Transient Receptor Potential (TRP) Cation Channels; Volume I Bernd Nilius,Veit Flockerzi Book 2014 Springer-Verlag Berlin Heidelb

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發(fā)表于 2025-3-21 17:46:12 | 只看該作者 |倒序瀏覽 |閱讀模式
書目名稱Mammalian Transient Receptor Potential (TRP) Cation Channels
副標題Volume I
編輯Bernd Nilius,Veit Flockerzi
視頻videohttp://file.papertrans.cn/623/622045/622045.mp4
概述Gives an excellent overview on mammalian TRP cation channels, a rapidly moving field.Written by outstanding authorities in the field.With numerous illustrations
叢書名稱Handbook of Experimental Pharmacology
圖書封面Titlebook: Mammalian Transient Receptor Potential (TRP) Cation Channels; Volume I Bernd Nilius,Veit Flockerzi Book 2014 Springer-Verlag Berlin Heidelb
描述In this fast moving field the main goal of this volume is to provide up-to-date information on the molecular and functional properties and pharmacology of mammalian TRP channels. Leading experts in the field will describe properties of a single TRP protein/channel or portray more general principles of TRP function and important pathological situations linked to mutations of TRP genes or their altered expression. Thereby this volume on Transient Receptor Potential (TRP) Channels provides valuable information for readers with different expectations and backgrounds, for those who are approaching this field of research as well as for those wanting to make a trip to TRPs.
出版日期Book 2014
關鍵詞Pain perception; TRP channels; TRP pharmacology; Temperature sensors
版次1
doihttps://doi.org/10.1007/978-3-642-54215-2
isbn_softcover978-3-662-51223-4
isbn_ebook978-3-642-54215-2Series ISSN 0171-2004 Series E-ISSN 1865-0325
issn_series 0171-2004
copyrightSpringer-Verlag Berlin Heidelberg 2014
The information of publication is updating

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TRPC1 predicted to consist of six transmembrane segments with the N- and C-termini located in the cytoplasm. The extracellular loop connecting transmembrane segments 5 and 6 participates in the formation of the ionic pore region. Inside the cell, TRPC1 is present in the endoplasmic reticulum, plasma memb
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TRPC2s including mice, rats, and New World monkeys, TRPC2 is a pseudogene in humans, apes, Old World monkeys, and in a number of other vertebrates. TRPC2 is highly expressed in the rodent VNO. It is also detectable at the protein level in murine erythroblasts, sperm, and brain and has been detected in ot
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TRPC3: A Multifunctional Signaling Moleculeas well as ambitious attempts to uncover its physiological role in native cell systems, the channel protein still represents a rather enigmatic member of the TRP superfamily. TRPC3 is significantly expressed in the brain and heart and appears of (patho)physiological importance in both non-excitable
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TRPC5l retardation. TRPC5 is a Ca.-permeable cation channel predominantly expressed in the CNS, including the hippocampus, cerebellum, amygdala, sensory neurons, and retina. It also shows more restricted expression in the periphery, notably in the kidney and cardiovascular system. Homotetrameric TRPC5 ch
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